日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation.

组织驻留巨噬细胞的存活依赖于线粒体功能,而线粒体功能在慢性炎症中受 SerpinB2 调控。

Vasamsetti Sathish Babu, Sadaf Samreen, Uddin Mohammad A, Shen Jixing, Johny Ebin, Mondal Awishi, Florentin Jonathan, Lei Liqun, Mannan Aleef, Rao Krithika Sudhakar, Sembrat John, Rojas Mauricio, Sipula Ian, Kastroll Jake, Jurczak Michael J, Shiva Sruti, O'Doherty Robert M, Yechoor Vijay, Dutta Partha

Mutation in IR or IGF1R produces features of long-lived mice while maintaining metabolic health

IR或IGF1R基因突变可使小鼠表现出长寿的特征,同时维持其代谢健康。

Hernández-Arciga, Ulalume; Kim, Jun Kyoung; Fisher, Jacob L; Tyshkovskiy, Alexander; Moldakozhayev, Alibek; Hall, Catherine; Ghosh, Souvik; Govindaraj, Yashvandhini; Sipula, Ian J; Kastroll, Jake; Cooke, Diana; Luo, Jinping; Alder, Jonathan K; Rizzo, Stacey J Sukoff; Ables, Gene P; Choi, Eunhee; Gladyshev, Vadim N; Jurczak, Michael J; Tatar, Marc; Parkhitko, Andrey A

Skeletal muscle mitochondrial dysfunction is associated with increased Gdf15 expression and circulating GDF15 levels in aged mice.

老年小鼠骨骼肌线粒体功能障碍与 Gdf15 表达增加和循环 GDF15 水平升高有关

Chen J, Kastroll J, Bello F M, Pangburn M M, Murali A, Smith P M, Rychcik K, Loughridge K E, Vandevender A M, Dedousis N, Sipula I J, Alder J K, Jurczak M J