AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts
AZD5438 是一种强效的口服细胞周期依赖性激酶 1、2 和 9 抑制剂,可在人类肿瘤异种移植中引起药效学变化并产生强效的抗肿瘤作用
期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-08-0836
Kate F Byth, Andrew Thomas, Gareth Hughes, Cheryl Forder, Alexandra McGregor, Catherine Geh, Sandra Oakes, Clive Green, Mike Walker, Nicholas Newcombe, Stephen Green, Jim Growcott, Andy Barker, Robert W Wilkinson