Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease
E2814是一种高亲和力抗体，靶向tau蛋白的微管结合重复结构域，用于阿尔茨海默病被动免疫治疗，本文对其进行了临床前表征。
期刊:Acta Neuropathologica Communications
影响因子:6.2
doi:10.1186/s40478-020-0884-2
Malcolm Roberts ,Ioanna Sevastou ,Yoichi Imaizumi ,Kavita Mistry ,Sonia Talma ,Madhurima Dey ,Jane Gartlon ,Hiroshi Ochiai ,Zhi Zhou ,Shigeru Akasofu ,Naoki Tokuhara ,Makoto Ogo ,Muneo Aoyama ,Hirofumi Aoyagi ,Kate Strand ,Ezat Sajedi ,Kishan Lal Agarwala ,Jared Spidel ,Earl Albone ,Kanta Horie ,James M Staddon ,Rohan de Silva
