日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterization of a 3S PRAME VLD-Specific T Cell Receptor and Its Use in Investigational Medicinal Products for TCR-T Therapy of Patients with Myeloid Malignancies

3S PRAME VLD 特异性 T 细胞受体的表征及其在髓系恶性肿瘤患者 TCR-T 治疗试验药物中的应用

Maja Bürdek, Petra U Prinz, Kathrin Mutze, Stefanie Tippmer, Christiane Geiger, Giulia Longinotti, Dolores J Schendel

T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and Strong Anti-Tumor Reactivity

表达高效 PRAME 特异性 T 细胞受体的 T 细胞与嵌合 PD1-41BB 共刺激受体结合,表现出良好的临床前安全性和强大的抗肿瘤反应性

Nadja Sailer, Ina Fetzer, Melanie Salvermoser, Monika Braun, Doris Brechtefeld, Christian Krendl, Christiane Geiger, Kathrin Mutze, Elfriede Noessner, Dolores J Schendel, Maja Bürdek, Susanne Wilde, Daniel Sommermeyer

microRNA Expression Profile of Purified Alveolar Epithelial Type II Cells

纯化肺泡上皮 II 型细胞的 microRNA 表达谱

Stefan Dehmel, Katharina J Weiss, Natalia El-Merhie, Jens Callegari, Birte Konrad, Kathrin Mutze, Oliver Eickelberg, Melanie Königshoff, Susanne Krauss-Etschmann

Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis

尼达尼布和吡非尼酮对肺纤维化小鼠和人肺组织培养物中肺泡上皮细胞功能的不同影响

Mareike Lehmann, Lara Buhl, Hani N Alsafadi, Stephan Klee, Sarah Hermann, Kathrin Mutze, Chiharu Ota, Michael Lindner, Jürgen Behr, Anne Hilgendorff, Darcy E Wagner, Melanie Königshoff

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

衰老细胞清除药物靶向肺泡上皮细胞功能,并在体外减轻实验性肺纤维化。

Mareike Lehmann ,Martina Korfei ,Kathrin Mutze ,Stephan Klee ,Wioletta Skronska-Wasek ,Hani N Alsafadi ,Chiharu Ota ,Rita Costa ,Herbert B Schiller ,Michael Lindner ,Darcy E Wagner ,Andreas Günther ,Melanie Königshoff

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

非经典 WNT-5A 信号损害 COPD 中的内源性肺修复

Hoeke A Baarsma, Wioletta Skronska-Wasek, Kathrin Mutze, Florian Ciolek, Darcy E Wagner, Gerrit John-Schuster, Katharina Heinzelmann, Andreas Günther, Ken R Bracke, Maylis Dagouassat, Jorge Boczkowski, Guy G Brusselle, Ron Smits, Oliver Eickelberg, Ali Ö Yildirim, Melanie Königshoff

No involvement of alveolar macrophages in the initiation of carbon nanoparticle induced acute lung inflammation in mice

肺泡巨噬细胞不参与小鼠碳纳米粒子诱发的急性肺部炎症的启动

Shanze Chen, Renfu Yin, Kathrin Mutze, Youjia Yu, Shinji Takenaka, Melanie Königshoff, Tobias Stoeger

Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility

辅激活剂相关精氨酸甲基转移酶-1 在肺泡上皮衰老和弹性蛋白酶诱发的肺气肿易感性中的作用

Rim S J Sarker, Gerrit John-Schuster, Alexander Bohla, Kathrin Mutze, Gerald Burgstaller, Mark T Bedford, Melanie Königshoff, Oliver Eickelberg, Ali Ö Yildirim

Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells

烯醇化酶 1 (ENO1) 和蛋白质二硫键异构酶相关 3 (PDIA3) 调节 Wnt/β-catenin 驱动的小鼠肺泡上皮细胞转分化

Kathrin Mutze, Sarah Vierkotten, Jadranka Milosevic, Oliver Eickelberg, Melanie Königshoff