Single Amino Acid Substitutions at Specific Positions of the Heptad Repeat Sequence of Piscidin-1 Yielded Novel Analogs That Show Low Cytotoxicity and In Vitro and In Vivo Antiendotoxin Activity
在Piscidin-1七肽重复序列的特定位置进行单氨基酸替换,可得到新型类似物,这些类似物显示出低细胞毒性以及体外和体内抗内毒素活性。
期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02341-15
Kumar, Amit; Tripathi, Amit Kumar; Kathuria, Manoj; Shree, Sonal; Tripathi, Jitendra Kumar; Purshottam, R K; Ramachandran, Ravishankar; Mitra, Kalyan; Ghosh, Jimut Kanti