日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions

脑源性神经营养因子rs6265(Val66Met)多态性对周围神经再生治疗性电刺激的影响:治疗-基因型相互作用的临床前研究

Jordan B Walters ,Maria J Quezada ,Suning He ,Ciara S Haynes ,Kathy Steece-Collier ,Timothy J Collier ,Caryl E Sortwell ,Colin K Franz

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats

年龄增长和 rs6265 BDNF SNP 导致帕金森病大鼠发生移植物诱发的运动障碍

Natosha M Mercado #, Carlye Szarowicz #, Jennifer A Stancati, Caryl E Sortwell, Samuel A Boezwinkle, Timothy J Collier, Margaret E Caulfield, Kathy Steece-Collier

Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils

用预先形成的纤维诱导的大鼠早期突触核蛋白病的转录组分析

Joseph R Patterson ,Joseph Kochmanski ,Anna C Stoll ,Michael Kubik ,Christopher J Kemp ,Megan F Duffy ,Kajene Thompson ,Jacob W Howe ,Allyson Cole-Strauss ,Nathan C Kuhn ,Kathryn M Miller ,Seth Nelson ,Christopher U Onyekpe ,John S Beck ,Scott E Counts ,Alison I Bernstein ,Kathy Steece-Collier ,Kelvin C Luk ,Caryl E Sortwell

Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS

经过基因工程改造的AAV衣壳转运突变体克服了老年中枢神经系统中的转导缺陷。

Ivette M Sandoval ,Christy M Kelley ,Luis Daniel Bernal-Conde ,Kathy Steece-Collier ,David J Marmion ,Marcus Davidsson ,Sean M Crosson ,Sanford L Boye ,Shannon E Boye ,Fredric P Manfredsson

Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions

黑质反应性胶质细胞的神经炎症基因表达谱表明,针对α-突触核蛋白包涵体的免疫反应是多维度的。

Anna C Stoll ,Christopher J Kemp ,Joseph R Patterson ,Jacob W Howe ,Kathy Steece-Collier ,Kelvin C Luk ,Caryl E Sortwell ,Matthew J Benskey

Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein

β2-肾上腺素受体激动剂克伦特罗会导致 α-突触核蛋白 mRNA 暂时减少,但不会导致蛋白质长期减少

Joseph R Patterson, Warren D Hirst, Jacob W Howe, Christopher P Russell, Allyson Cole-Strauss, Christopher J Kemp, Megan F Duffy, Jared Lamp, Andrew Umstead, Michael Kubik, Anna C Stoll, Irving E Vega, Kathy Steece-Collier, Yi Chen, Anne C Campbell, Catherine L Nezich, Kelly E Glajch, Caryl E Sortwe

New Frontiers in Neurodegeneration and Regeneration Associated with Brain-Derived Neurotrophic Factor and the rs6265 Single Nucleotide Polymorphism

与脑源性神经营养因子和 rs6265 单核苷酸多态性相关的神经退行性疾病和再生的新前沿

Carlye A Szarowicz, Kathy Steece-Collier, Margaret E Caulfield

α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease

α-突触核蛋白反义寡核苷酸作为帕金森病的疾病改良疗法

Tracy A Cole, Hien Zhao, Timothy J Collier, Ivette Sandoval, Caryl E Sortwell, Kathy Steece-Collier, Brian F Daley, Alix Booms, Jack Lipton, Mackenzie Welch, Melissa Berman, Luke Jandreski, Danielle Graham, Andreas Weihofen, Stephanie Celano, Emily Schulz, Allyson Cole-Strauss, Esteban Luna, Duc Qua

The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats

BDNF Val66Met 多态性 (rs6265) 增强了 rs6265 敲入大鼠的多巴胺神经元移植功效和副作用倾向

Natosha M Mercado, Jennifer A Stancati, Caryl E Sortwell, Rebecca L Mueller, Samuel A Boezwinkle, Megan F Duffy, D Luke Fischer, Ivette M Sandoval, Fredric P Manfredsson, Timothy J Collier, Kathy Steece-Collier

Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS

纹状体传入 BDNF 因突触核蛋白病而中断,并通过 STN DBS 部分恢复

Kathryn M Miller, Joseph R Patterson, Joseph Kochmanski, Christopher J Kemp, Anna C Stoll, Christopher U Onyekpe, Allyson Cole-Strauss, Kathy Steece-Collier, Jacob W Howe, Kelvin C Luk, Caryl E Sortwell