Impaired clearance of apoptotic cells leads to HMGB1 release in the bone marrow of patients with myelodysplastic syndromes and induces TLR4-mediated cytokine production
骨髓增生异常综合征患者骨髓中凋亡细胞清除受损会导致HMGB1释放,并诱导TLR4介导的细胞因子生成。
期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2012.064642
Velegraki, Maria; Papakonstanti, Evaggelia; Mavroudi, Irene; Psyllaki, Maria; Tsatsanis, Christos; Oulas, Anastasis; Iliopoulos, Ioannis; Katonis, Pavlos; Papadaki, Helen A
凋亡
表观遗传
TLR4
HMGB1
细胞生物学
免疫/内分泌