日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A P5-ATPase, TgFLP12, diverging from plant chloroplast lipid transporters mediates apicoplast fatty export in Toxoplasma

一种与植物叶绿体脂质转运蛋白不同的P5-ATPase，TgFLP12，介导弓形虫顶质体中的脂肪输出。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-61155-9.
Christophe-Sébastien Arnold,Anna-Maria Alazzi,Serena Shunmugam,Jan Janouškovec,Laurence Berry,Sarah Charital,Thierry Gautier,Samuel Duley,Delphine Jublot,Catherine Lemaire-Vieille,Marie-France Cesbron-Delauw,Pierre Cavailles,Jérôme Govin,Nicholas J Katris,Yoshiki Yamaryo-Botté,Cyrille Y Botté
TPA
发表日期：2025
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Differentiation of Toxoplasma into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase

弓形虫分化为潜伏型与中心碳代谢有关，并且需要GID/CTLH型E3泛素连接酶。

期刊:
影响因子:
doi:10.1101/2025.07.27.667068
Uboldi, Alessandro D; Khurana, Sachin; Jaywickrama, Amalie A; Lekkala-Lethakula, Sai Prasanna; Simonpietri, Amber; Singh, Karan; Hofferek, Vinzenz; Ruparel, Ushma; Whitehead, Lachlan L; Rogers, Kelly L; Garnham, Alexandra L; Scott, Nichollas; Katris, Nicholas J; McConville, Malcolm J; Komander, David; Cobbold, Simon A; Tonkin, Christopher J
代谢
发表日期：2025
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The acyl-CoA synthetase Tg ACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions

在低营养条件下，酰基辅酶A合成酶Tg ACS1通过其过氧化物酶体靶向序列（PTS）的重定位，使弓形虫能够进行中性脂质代谢和胞外运动。

期刊:mBio
影响因子:5.1
doi:10.1128/mbio.00427-24
Sarah Charital #,Serena Shunmugam #,Sheena Dass,Anna Maria Alazzi,Christophe-Sébastien Arnold,Nicholas J Katris,Samuel Duley,Nyamekye A Quansah,Fabien Pierrel,Jérôme Govin,Yoshiki Yamaryo-Botté,Cyrille Y Botté
代谢
发表日期：2024
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Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation

弓形虫酰基辅酶A合成酶TgACS3对于将宿主脂肪酸输送到脂滴中以及寄生虫的繁殖至关重要。

期刊:Journal of Lipid Research
影响因子:4.1
doi:10.1016/j.jlr.2024.100645
Dass, Sheena; Shunmugam, Serena; Charital, Sarah; Duley, Samuel; Arnold, Christophe-Sébastien; Katris, Nicholas J; Cavaillès, Pierre; Cesbron-Delauw, Marie-France; Yamaryo-Botté, Yoshiki; Botté, Cyrille Y
微生物学
代谢
发表日期：2024
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Toxoplasma metabolic flexibility in different growth conditions

弓形虫在不同生长条件下的代谢灵活性

期刊:Trends in Parasitology
影响因子:6.6
doi:10.1016/j.pt.2022.06.001
Walsh, Daniel; Katris, Nicholas J; Sheiner, Lilach; Botté, Cyrille Y
代谢
发表日期：2022
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A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signalling in calcium-induced Toxoplasma gondii egress

正反馈回路介导钙、环核苷酸和脂质信号在钙诱导的弓形虫排出过程中的串扰

期刊:PLoS Pathogens
影响因子:5.5
doi:10.1371/journal.ppat.1010901
Stephanie D Nofal, Caia Dominicus, Malgorzata Broncel, Nicholas J Katris, Helen R Flynn, Gustavo Arrizabalaga, Cyrille Y Botté, Brandon M Invergo, Moritz Treeck
信号转导
GPCR/Calcium/cAMP
发表日期：2022
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The flexibility of Apicomplexa parasites in lipid metabolism

顶复门寄生虫脂质代谢的灵活性

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1010313
Shunmugam, Serena; Arnold, Christophe-Sébastien; Dass, Sheena; Katris, Nicholas J; Botté, Cyrille Y
微生物学
代谢
发表日期：2022
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Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage

弓形虫 LIPIN 在通过膜生物合成和脂质储存来引导宿主脂质流方面至关重要

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-021-22956-w
Dass, Sheena; Shunmugam, Serena; Berry, Laurence; Arnold, Christophe-Sebastien; Katris, Nicholas J; Duley, Samuel; Pierrel, Fabien; Cesbron-Delauw, Marie-France; Yamaryo-Botté, Yoshiki; Botté, Cyrille Y
发表日期：2021
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An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca(2+) signaling and motility in Toxoplasma gondii

位于顶端的杂合鸟苷酸环化酶-ATP酶对于弓形虫中Ca(2+)信号的启动和运动至关重要

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.005491
Yang, Luning; Uboldi, Alessandro D; Seizova, Simona; Wilde, Mary-Louise; Coffey, Michael J; Katris, Nicholas J; Yamaryo-Botté, Yoshiki; Kocan, Martina; Bathgate, Ross A D; Stewart, Rebecca J; McConville, Malcolm J; Thompson, Philip E; Botté, Cyrille Y; Tonkin, Christopher J
信号转导
发表日期：2019
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Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii

蛋白激酶A负调控弓形虫中的Ca2+信号传导

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.2005642
Uboldi, Alessandro D; Wilde, Mary-Louise; McRae, Emi A; Stewart, Rebecca J; Dagley, Laura F; Yang, Luning; Katris, Nicholas J; Hapuarachchi, Sanduni V; Coffey, Michael J; Lehane, Adele M; Botte, Cyrille Y; Waller, Ross F; Webb, Andrew I; McConville, Malcolm J; Tonkin, Christopher J
信号转导
发表日期：2018
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