日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

阻断 AMPK β1 肉豆蔻酰化可增强 AMPK 活性并保护小鼠免受高脂饮食引起的肥胖和肝脂肪变性

Katyayanee Neopane, Natalie Kozlov, Florentina Negoita, Lisa Murray-Segal, Robert Brink, Ashfaqul Hoque, Ashley J Ovens, Gavin Tjin, Luke M McAloon, Dingyi Yu, Naomi X Y Ling, Matthew J Sanders, Jonathan S Oakhill, John W Scott, Gregory R Steinberg, Kim Loh, Bruce E Kemp, Kei Sakamoto, Sandra Galic

Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite-binding site

天然(二氢)菲类植物化合物通过其变构药物和代谢物结合位点直接激活AMPK。

Matthew J Sanders ,Yann Ratinaud ,Katyayanee Neopane ,Nicolas Bonhoure ,Emily A Day ,Olivier Ciclet ,Steve Lassueur ,Martine Naranjo Pinta ,Maria Deak ,Benjamin Brinon ,Stefan Christen ,Gregory R Steinberg ,Denis Barron ,Kei Sakamoto

Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

ULK1/AMPK抑制剂SBI-0206965的特异性及作用机制研究

Danial Ahwazi #, Katyayanee Neopane #, Greg R Markby, Franziska Kopietz, Ashley J Ovens, Morten Dall, Anna S Hassing, Pamina Gräsle, Yazeed Alshuweishi, Jonas T Treebak, Ian P Salt, Olga Göransson, Elton Zeqiraj, John W Scott, Kei Sakamoto

Targeted Protein Degradation through Cytosolic Delivery of Monobody Binders Using Bacterial Toxins

利用细菌毒素将单克隆抗体结合剂递送至胞质,实现靶向蛋白质降解

Nadine Eliane Schmit ,Katyayanee Neopane ,Oliver Hantschel