日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B

在嗜中性粒细胞减少的小鼠肺毛霉菌病模型中,伊布沙芬普作为单药治疗以及与脂质体两性霉素B联合治疗均有效。

Gebremariam, Teclegiorgis; Alkhazraji, Sondus; Gu, Yiyou; Najvar, Laura K; Borroto-Esoda, Katyna; Patterson, Thomas F; Filler, Scott G; Wiederhold, Nathan P; Ibrahim, Ashraf S

SARS-CoV-2 viral dynamics in a placebo-controlled phase 2 study of patients infected with the SARS-CoV-2 Omicron variant and treated with pomotrelvir

在一项安慰剂对照的 2 期研究中,感染 SARS-CoV-2 Omicron 变异株并接受 pomotrelvir 治疗的患者体内 SARS-CoV-2 病毒动力学的变化

Borroto-Esoda, Katyna; Wilfret, David; Tong, Xiao; Plummer, Andrew; Kearney, Brian; Kwong, Ann D

Discovering the mechanism of action of drugs with a sparse explainable network

利用稀疏可解释网络发现药物的作用机制

Sada Del Real, Katyna; Rubio, Angel

Precision oncology: a review to assess interpretability in several explainable methods

精准肿瘤学:评估几种可解释方法的可解释性的综述

Gimeno, Marian; Sada Del Real, Katyna; Rubio, Angel

A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

一项针对 COVID-19 患者的 2a 期临床试验表明,莫努匹韦可加速 SARS-CoV-2 RNA 的清除并消除传染性病毒。

Fischer, William A 2nd; Eron, Joseph J Jr; Holman, Wayne; Cohen, Myron S; Fang, Lei; Szewczyk, Laura J; Sheahan, Timothy P; Baric, Ralph; Mollan, Katie R; Wolfe, Cameron R; Duke, Elizabeth R; Azizad, Masoud M; Borroto-Esoda, Katyna; Wohl, David A; Coombs, Robert W; James Loftis, Amy; Alabanza, Paul; Lipansky, Felicia; Painter, Wendy P

Ibrexafungerp Versus Placebo for Vulvovaginal Candidiasis Treatment: A Phase 3, Randomized, Controlled Superiority Trial (VANISH 303)

伊布沙芬普与安慰剂治疗外阴阴道念珠菌病:一项 3 期随机对照优效性试验 (VANISH 303)

Schwebke, Jane R; Sobel, Ryan; Gersten, Janet K; Sussman, Steven A; Lederman, Samuel N; Jacobs, Mark A; Chappell, B Todd; Weinstein, David L; Moffett, Alfred H; Azie, Nkechi E; Angulo, David A; Harriott, Itzel A; Borroto-Esoda, Katyna; Ghannoum, Mahmoud A; Nyirjesy, Paul; Sobel, Jack D

In Vitro Antifungal Activity of Ibrexafungerp (SCY-078) Against Contemporary Blood Isolates From Medically Relevant Species of Candida: A European Study

体外抗真菌药物Ibrexafungerp (SCY-078) 对当代医学相关念珠菌血液分离株的抗真菌活性:一项欧洲研究

Quindós, Guillermo; Miranda-Cadena, Katherine; San-Millán, Rosario; Borroto-Esoda, Katyna; Cantón, Emilia; Linares-Sicilia, María José; Hamprecht, Axel; Montesinos, Isabel; Tortorano, Anna Maria; Prigitano, Anna; Vidal-García, Matxalen; Marcos-Arias, Cristina; Guridi, Andrea; Sanchez-Reus, Ferran; Machuca-Bárcena, Jesús; Rodríguez-Iglesias, Manuel Antonio; Martín-Mazuelos, Estrella; Castro-Méndez, Carmen; López-Soria, Leyre; Ruiz-Gaitán, Alba; Fernandez-Rivero, Marcelo; Lorenzo, Damaris; Capilla, Javier; Rezusta, Antonio; Pemán, Javier; Guarro, Josep; Pereira, Joana; Pais, Célia; Romeo, Orazio; Ezpeleta, Guillermo; Jauregizar, Nerea; Angulo, David; Eraso, Elena

Investigating the Antituberculosis Activity of Selected Commercial Essential Oils and Identification of Active Constituents Using a Biochemometrics Approach and In Silico Modeling

利用生物化学计量学方法和计算机模拟技术研究几种市售精油的抗结核活性并鉴定其活性成分

Boussamba-Digombou, Katyna J; Sandasi, Maxleene; Kamatou, Guy P; van Vuuren, Sandy; Sawicki, Rafal; Fakhar, Zeynab; Viljoen, Alvaro M

Ibrexafungerp, a Novel Oral Triterpenoid Antifungal in Development: Overview of Antifungal Activity Against Candida glabrata

伊布沙芬普(Ibrexafungerp),一种正在研发中的新型口服三萜类抗真菌药物:针对光滑念珠菌的抗真菌活性概述

Gamal, Ahmed; Chu, Sherman; McCormick, Thomas S; Borroto-Esoda, Katyna; Angulo, David; Ghannoum, Mahmoud A

A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates

第二代 Fungerp 类似物 SCY-247 对耳念珠菌和其他临床相关真菌分离株显示出强大的体外活性

Chu, Sherman; Long, Lisa; Sherif, Rania; McCormick, Thomas S; Borroto-Esoda, Katyna; Barat, Stephen; Ghannoum, Mahmoud A