日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy

利用结构导向方法,从超大化学空间中发现CHI3L1抑制剂用于胶质母细胞瘤治疗

Kaur, Baljit; Sindt, François; Zhang, Longfei; Rognan, Didier; Gabr, Moustafa

Targeting CHI3L1 in Alzheimer's Disease: Optimization of G721-0282 and Functional Evaluation in Astrocyte Models

靶向 CHI3L1 治疗阿尔茨海默病:G721-0282 的优化及在星形胶质细胞模型中的功能评价

Kaur, Baljit; Nada, Hossam; Zhang, Longfei; Gabr, Moustafa

TREM2 and LAG-3 in cancer and Alzheimer's disease immunotherapy

TREM2 和 LAG-3 在癌症和阿尔茨海默病免疫疗法中的作用

Yuan, Shaoren; Fuchs, Natalie S; Abdel-Rahman, Somaya A; Kaur, Baljit; Gabr, Moustafa T

CHI3L1-targeted small molecules as glioblastoma therapies: Virtual screening-based discovery, biophysical validation, pharmacokinetic profiling, and evaluation in glioblastoma spheroids.

以 CHI3L1 为靶点的小分子作为胶质母细胞瘤疗法:基于虚拟筛选的发现、生物物理验证、药代动力学分析和在胶质母细胞瘤球体中的评估

Nada Hossam, Zhang Longfei, Kaur Baljit, Gabr Moustafa T

Virtual Screening-Guided Discovery of Small-Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma Spheroids

虚拟筛选指导下发现对胶质母细胞瘤球体具有功能活性的CHI3L1小分子抑制剂

Kaur, Baljit; Denzinger, Katrin; Zhang, Longfei; García-Vázquez, Nelson; Wolber, Gerhard; Gabr, Moustafa

Is Primary Opening of Fistula-in-Ano Always at Dentate Line: Correlation Between MRI and Operative Findings in 379 Patients

肛瘘原发开口是否总是位于齿状线:379例患者的MRI与手术发现的相关性研究

Garg, Pankaj; Naldini, Gabriele; De Parades, Vincent; Tsarkov, Petr; Yagnik, Vipul D; Bhattacharya, Kaushik; Kaur, Baljit; Mahak, G

CD28 and ICOS in immune regulation: Structural insights and therapeutic targeting

CD28 和 ICOS 在免疫调节中的作用:结构解析和治疗靶点

Upadhyay, Saurabh; Kaur, Baljit; Gabr, Moustafa T

Process to determine the level of the primary internal opening of anal fistula on magnetic resonance imaging

通过磁共振成像确定肛瘘原发性内口位置的过程

Garg, Pankaj; Kaur, Baljit; Mahak, G

Structure-Based Virtual Screening Identifies TREM2-Targeted Small Molecules that Enhance Microglial Phagocytosis

基于结构的虚拟筛选鉴定出靶向TREM2的小分子,这些小分子可增强小胶质细胞的吞噬作用

Cho, Sungwoo; Kaur, Baljit; Lam, Kevin; Gaamouch, Farida El; Kuncewicz, Katarzyna; Doering, Niklas Piet; Wolber, Gerhard; Gabr, Moustafa T

Virtual Screening-Guided Discovery of Small Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma Spheroids

虚拟筛选指导下发现对胶质母细胞瘤球体具有功能活性的CHI3L1小分子抑制剂

Kaur, Baljit; Denzinger, Katrin; Zhang, Longfei; Garcia-Vazquez, Nelson; Wolber, Gerhard; Gabr, Moustafa