日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins

Elamipretide (SS-31) 治疗可减轻与年龄相关的心脏蛋白质翻译后修饰

Whitson, Jeremy A; Martín-Pérez, Miguel; Zhang, Tong; Gaffrey, Matthew J; Merrihew, Gennifer E; Huang, Eric; White, Collin C; Kavanagh, Terrance J; Qian, Wei-Jun; Campbell, Matthew D; MacCoss, Michael J; Marcinek, David J; Villén, Judit; Rabinovitch, Peter S

The effects of gene × environment interactions on silver nanoparticle toxicity in the respiratory system: An adverse outcome pathway

基因与环境相互作用对银纳米颗粒呼吸系统毒性的影响:一条不良结局途径

Nicholas, Tyler P; Boyes, William K; Scoville, David K; Workman, Tomomi W; Kavanagh, Terrance J; Altemeier, William A; Faustman, Elaine M

Vitamin C is a source of oxoaldehyde and glycative stress in age-related cataract and neurodegenerative diseases

维生素C是与年龄相关的白内障和神经退行性疾病中羰基醛和糖化应激的来源。

Fan, Xingjun; Sell, David R; Hao, Caili; Liu, Sabrina; Wang, Benlian; Wesson, Daniel W; Siedlak, Sandra; Zhu, Xiongwei; Kavanagh, Terrance J; Harrison, Fiona E; Monnier, Vincent M

The Effects of Genotype × Phenotype Interactions on Transcriptional Response to Silver Nanoparticle Toxicity in Organotypic Cultures of Murine Tracheal Epithelial Cells

基因型×表型相互作用对小鼠气管上皮细胞器官型培养物中银纳米颗粒毒性转录反应的影响

Nicholas, Tyler P; Haick, Anoria K; Bammler, Theo K; Workman, Tomomi W; Kavanagh, Terrance J; Faustman, Elaine M; Gharib, Sina A; Altemeier, William A

Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified

羰基还原酶1在小鼠肝脏中将阿霉素转化为具有心脏毒性的阿霉素醇的过程中起着重要作用,但大部分阿霉素醇的形成活性仍未被鉴定。

Breysse, Daniel H; Boone, Ryan M; Long, Cameron M; Merrill, Miranda E; Schaupp, Christopher M; White, Collin C; Kavanagh, Terrance J; Schmidt, Edward E; Merrill, Gary F

CRISPR-Generated Nrf2a Loss- and Gain-of-Function Mutants Facilitate Mechanistic Analysis of Chemical Oxidative Stress-Mediated Toxicity in Zebrafish

利用 CRISPR 技术构建的 Nrf2a 功能缺失和功能获得突变体有助于对斑马鱼化学氧化应激介导的毒性机制进行分析

Mills, Margaret G; Ramsden, Richard; Ma, Eva Y; Corrales, Jone; Kristofco, Lauren A; Steele, W Baylor; Saari, Gavin N; Melnikov, Fjodor; Kostal, Jakub; Kavanagh, Terrance J; Zimmerman, Julie B; Voutchkova-Kostal, Adelina M; Brooks, Bryan W; Coish, Philip; Anastas, Paul T; Gallagher, Evan

The effects of genotype × phenotype interactions on silver nanoparticle toxicity in organotypic cultures of murine tracheal epithelial cells

基因型×表型相互作用对小鼠气管上皮细胞器官型培养物中银纳米颗粒毒性的影响

Nicholas, Tyler P; Haick, Anoria K; Workman, Tomomi W; Griffith, William C; Nolin, James D; Kavanagh, Terrance J; Faustman, Elaine M; Altemeier, William A

Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule expression, and TGF-β1 secretion

银纳米颗粒会改变上皮基底膜的完整性、细胞粘附分子的表达以及TGF-β1的分泌。

Martin, Megan E; Reaves, Denise K; Jeffcoat, Breanna; Enders, Jeffrey R; Costantini, Lindsey M; Yeyeodu, Susan T; Botta, Diane; Kavanagh, Terrance J; Fleming, Jodie M

Kinetics of Glutathione Depletion and Antioxidant Gene Expression as Indicators of Chemical Modes of Action Assessed in Vitro in Mouse Hepatocytes with Enhanced Glutathione Synthesis

谷胱甘肽消耗动力学和抗氧化基因表达作为化学作用模式的指标,在体外小鼠肝细胞中评估,这些细胞具有增强的谷胱甘肽合成能力

Melnikov, Fjodor; Botta, Dianne; White, Collin C; Schmuck, Stefanie C; Winfough, Matthew; Schaupp, Christopher M; Gallagher, Evan P; Brooks, Bryan W; Williams, Edward Spencer; Coish, Philip; Anastas, Paul T; Voutchkova-Kostal, Adelina; Kostal, Jakub; Kavanagh, Terrance J

Quantum dots and mouse strain influence house dust mite-induced allergic airway disease

量子点和鼠株对屋尘螨诱发的过敏性气道疾病有影响

Scoville, David K; Nolin, James D; Ogden, H Luke; An, Dowon; Afsharinejad, Zahra; Johnson, Brian W; Bammler, Theo K; Gao, Xiaohu; Frevert, Charles W; Altemeier, William A; Hallstrand, Teal S; Kavanagh, Terrance J