日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural heterogeneity and substrate engagement mechanism of the bacterial proteasome activator Bpa

细菌蛋白酶体激活剂Bpa的结构异质性和底物结合机制

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69978-w
Davis, Bradley T V; Rennella, Enrico; Haris, Anisha; Ujma, Jakub; Bruton, David; Richardson, Keith; Giles, Kevin; Kay, Lewis E; Vahidi, Siavash
微生物学
发表日期：2026
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Making invisible excited-state structures of pro-interleukin-18 visible by combining NMR and machine learning

结合核磁共振和机器学习技术，使白细胞介素-18前体的不可见激发态结构可见

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2537014123
Bonin, Jeffrey P; Lee, Jin Sub; Liu, Zi Hao; Kim, Philip M; Kay, Lewis E
细胞生物学
发表日期：2026
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Using CEST NMR to discover previously unobserved states on the free energy surface of proteins: Application to the L99A cavity mutant of T4 lysozyme

利用CEST NMR发现蛋白质自由能面上先前未观察到的状态：以T4溶菌酶L99A空腔突变体为例

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110989
Tiwari, Ved Prakash; Khandave, Nihar Pradeep; Hansen, D Flemming; Bouvignies, Guillaume; Kay, Lewis E; Vallurupalli, Pramodh
发表日期：2026
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The dynamic and heterogeneous structure of the non-canonical inflammasome

非经典炎症小体的动态和异质性结构

期刊:
影响因子:
doi:10.64898/2026.04.15.718739
Sever, Alexander I M; Aramini, James M; Bonin, Jeffrey P; Zhao, Huaying; Wang, Hanlin; Rubinstein, John L; Schuck, Peter; Kay, Lewis E
炎性小体
炎性小体
炎症/感染
免疫/内分泌
炎症
发表日期：2026
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Modulation of histone tail electrostatic potentials in nucleosome core particles by acetylation and PARylation

乙酰化和PARylation对核小体核心颗粒中组蛋白尾部静电势的调节

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2511507122
Bolik-Coulon, Nicolas; Rößler, Philip; Nosella, Michael L; Kim, Tae Hun; Kay, Lewis E
表观遗传
乙酰化
发表日期：2025
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Client-scaffold interactions suppress aggregation of a client protein in model condensates

客户-支架相互作用抑制模型凝聚体中客户蛋白的聚集。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2508403122
Ahmed, Rashik; Hudson, Rhea P; Forman-Kay, Julie D; Kay, Lewis E
发表日期：2025
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Dynamic conformational equilibria in the active states of KRAS and NRAS

KRAS和NRAS活性状态下的动态构象平衡

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d4cb00233d
Rennella, Enrico; Henry, Chrystèle; Dickson, Callum J; Georgescauld, Florian; Wales, Thomas E; Erdmann, Dirk; Cotesta, Simona; Maira, Michel; Sedrani, Richard; Brachmann, Saskia M; Ostermann, Nils; Engen, John R; Kay, Lewis E; Beyer, Kim S; Wilcken, Rainer; Jahnke, Wolfgang
RAS
发表日期：2025
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Structural transitions enable interleukin-18 maturation and signaling.

结构转变促进白细胞介素-18的成熟和信号传导

期刊:Immunity
影响因子:26.3
doi:10.1016/j.immuni.2024.04.015
Dong Ying, Bonin Jeffrey P, Devant Pascal, Liang Zhuoyi, Sever Alexander I M, Mintseris Julian, Aramini James M, Du Gang, Gygi Stephen P, Kagan Jonathan C, Kay Lewis E, Wu Hao
信号转导
细胞生物学
发表日期：2024
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Atomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates

CAPRIN1凝聚体中驱动SOD1展开的溶剂相互作用的原子分辨率图谱

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2408554121
Ahmed, Rashik; Liang, Mingyang; Hudson, Rhea P; Rangadurai, Atul K; Huang, Shuya Kate; Forman-Kay, Julie D; Kay, Lewis E
SOD1
APR
发表日期：2024
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Mapping the FF domain folding pathway via structures of transiently populated folding intermediates

通过瞬时存在的折叠中间体的结构来绘制FF结构域的折叠路径

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2416682121
De, Debajyoti; Thapliyal, Nemika; Prakash Tiwari, Ved; Toyama, Yuki; Flemming Hansen, D; Kay, Lewis E; Vallurupalli, Pramodh
发表日期：2024
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