日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis for antibody recognition of the proximal MUC16 ectodomain

抗体识别近端 MUC16 胞外域的结构基础

Kwangkook Lee, Kay Perry, Mengyao Xu, Irva Veillard, Raj Kumar, Thapi Dharma Rao, Bo R Rueda, David R Spriggs #, Oladapo O Yeku #

Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2

肉毒杆菌毒素 E 识别突触囊泡蛋白 2 的结构基础

Zheng Liu, Pyung-Gang Lee, Nadja Krez, Kwok-Ho Lam, Hao Liu, Adina Przykopanski, Peng Chen, Guorui Yao, Sicai Zhang, Jacqueline M Tremblay, Kay Perry, Charles B Shoemaker, Andreas Rummel, Min Dong, Rongsheng Jin

Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies

两种骆驼科 VHH 抗体的结构揭示艰难梭菌毒素 A 的中和表位

Baohua Chen, Kay Perry, Rongsheng Jin

Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies

使用单域抗体探索肉毒杆菌毒素蛋白酶结构域的结构和功能

Kwok-Ho Lam, Jacqueline M Tremblay, Kay Perry, Konstantin Ichtchenko, Charles B Shoemaker, Rongsheng Jin

Structure and conformational dynamics of Clostridioides difficile toxin A

艰难梭菌毒素 A 的结构和构象动力学

Baohua Chen, Sujit Basak, Peng Chen, Changcheng Zhang, Kay Perry, Songhai Tian, Clinton Yu, Min Dong, Lan Huang, Mark E Bowen, Rongsheng Jin

ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

ROR 和 RYK 胞外区结构表明受体酪氨酸激酶具有不同的 WNT 识别模式

Fumin Shi, Jeannine M Mendrola, Joshua B Sheetz, Neo Wu, Anselm Sommer, Kelsey F Speer, Jasprina N Noordermeer, Zhong-Yuan Kan, Kay Perry, S Walter Englander, Steven E Stayrook, Lee G Fradkin, Mark A Lemmon

Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins

基于单域抗体的抗肉毒杆菌神经毒素的合理设计的结构解析

Kwok-Ho Lam ,Jacqueline M Tremblay ,Edwin Vazquez-Cintron ,Kay Perry ,Celinia Ondeck ,Robert P Webb ,Patrick M McNutt ,Charles B Shoemaker ,Rongsheng Jin

Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells

两种 VHH 抗体通过阻断肉毒杆菌毒素 E1 在宿主细胞中的膜易位来中和该毒素

Kwok-Ho Lam, Kay Perry, Charles B Shoemaker, Rongsheng Jin

X-ray and cryo-EM structures of the mitochondrial calcium uniporter

线粒体钙单向转运体的 X 射线和低温电子显微镜结构

Chao Fan #, Minrui Fan #, Benjamin J Orlando #, Nathan M Fastman #, Jinru Zhang, Yan Xu, Melissa G Chambers, Xiaofang Xu, Kay Perry, Maofu Liao, Liang Feng

Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass

适体与药物的组合用于体外循环中的可逆性抗凝

Ruwan Gunaratne, Shekhar Kumar, James W Frederiksen, Steven Stayrook, Jens L Lohrmann, Kay Perry, Kristin M Bompiani, Charlene V Chabata, Nabil K Thalji, Michelle D Ho, Gowthami Arepally, Rodney M Camire, Sriram Krishnaswamy, Bruce A Sullenger