日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unexpected roles for AMPK in the suppression of autophagy and the reactivation of MTORC1 signaling during prolonged amino acid deprivation

AMPK在长期氨基酸缺乏期间抑制自噬和重新激活MTORC1信号通路中发挥意想不到的作用

Dubek Kazyken ,Sydney G Dame ,Claudia Wang ,Maxwell Wadley ,Diane C Fingar

Unexpected roles for AMPK in the suppression of autophagy and the reactivation of mTORC1 signaling during prolonged amino acid deprivation

AMPK在长期氨基酸缺乏期间抑制自噬和重新激活mTORC1信号通路中发挥意想不到的作用

Kazyken, Dubek; Dame, Sydney G; Wang, Claudia; Wadley, Maxwell; Fingar, Diane C

Alkaline intracellular pH (pHi) increases PI3K activity to promote mTORC1 and mTORC2 signaling and function during growth factor limitation

碱性细胞内 pH (pHi) 可增加 PI3K 活性,从而促进 mTORC1 和 mTORC2 信号传导和生长因子限制期间的功能

Dubek Kazyken, Stephen I Lentz, Maxwell Wadley, Diane C Fingar

TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance

TBK1-mTOR 信号减弱肥胖相关的高血糖症和胰岛素抵抗

Cagri Bodur, Dubek Kazyken, Kezhen Huang, Aaron Seth Tooley, Kae Won Cho, Tammy M Barnes, Carey N Lumeng, Martin G Myers, Diane C Fingar

Alkaline intracellular pH (pHi) activates AMPK-mTORC2 signaling to promote cell survival during growth factor limitation

碱性细胞内 pH (pHi) 激活 AMPK-mTORC2 信号,在生长因子受限期间促进细胞存活

D Kazyken, S I Lentz, D C Fingar

The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt

先天免疫激酶 TBK1 直接增加 mTORC2 活性和下游 Akt 信号传导

Aaron Seth Tooley, Dubek Kazyken, Cagri Bodur, Ian E Gonzalez, Diane C Fingar

The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation

GATOR2-mTORC2 轴介导 Sestrin2 诱导的 AKT Ser/Thr 激酶活化

Allison Ho Kowalsky, Sim Namkoong, Eric Mettetal, Hwan-Woo Park, Dubek Kazyken, Diane C Fingar, Jun Hee Lee

AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

AMPK 直接激活 mTORC2 以促进急性能量应激期间的细胞存活

Dubek Kazyken, Brian Magnuson, Cagri Bodur, Hugo A Acosta-Jaquez, Deqiang Zhang, Xin Tong, Tammy M Barnes, Gabrielle K Steinl, Nicole E Patterson, Christopher H Altheim, Naveen Sharma, Ken Inoki, Gregory D Cartee, Dave Bridges, Lei Yin, Steven M Riddle, Diane C Fingar

The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists

IKK相关激酶TBK1在生长因子和先天免疫激动剂的刺激下直接激活mTORC1。

Cagri Bodur ,Dubek Kazyken ,Kezhen Huang ,Bilgen Ekim Ustunel ,Kate A Siroky ,Aaron Seth Tooley ,Ian E Gonzalez ,Daniel H Foley ,Hugo A Acosta-Jaquez ,Tammy M Barnes ,Gabrielle K Steinl ,Kae-Won Cho ,Carey N Lumeng ,Steven M Riddle ,Martin G Myers Jr ,Diane C Fingar

The nuclear import of ribosomal proteins is regulated by mTOR

核糖体蛋白的核输入受 mTOR 调控

Dubek Kazyken, Yelimbek Kaz, Vladimir Kiyan, Assylbek A Zhylkibayev, Chien-Hung Chen, Nitin K Agarwal, Dos D Sarbassov