日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiomic screening platform uncovers the impact of histone mutations on chromatin and cell fate

多组学筛选平台揭示组蛋白突变对染色质和细胞命运的影响

Ye, Ziyang; Khademi, Alireza; Barbosa, Renée L; Birnbaum, Foster; Brown, Margaret R; Fowler, Colin E; Arroyo-Ortega, Arianna; Lee, Daniel; Feng, Lijuan; Gates, Leah A; Patriotis, Agata L; Keating, Amy E; Sánchez-Rivera, Francisco J; Soto-Feliciano, Yadira M

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

蛋白质组范围的生化筛选确定了核心自噬蛋白LC3B的结合决定簇

Kosmatka, Jennifer; Liu, Cong; Halpin, Jackson C; Lim, Daniel; Davis, Joseph H; Keating, Amy E

Beyond native sequence recovery: Improved modeling of the sequence-energy landscape of protein structures

超越天然序列恢复:改进蛋白质结构序列能量景观的建模

Birnbaum, Foster; Keating, Amy E

High-throughput discovery of inhibitory protein fragments with AlphaFold

利用 AlphaFold 进行抑制性蛋白片段的高通量发现

Savinov, Andrew; Swanson, Sebastian; Keating, Amy E; Li, Gene-Wei

Training bias and sequence alignments shape protein-peptide docking by AlphaFold and related methods

训练偏差和序列比对会影响 AlphaFold 及相关方法的蛋白质-肽对接结果

Guan, Lindsey; Keating, Amy E

PairK: Pairwise k-mer alignment for quantifying protein motif conservation in disordered regions

PairK:用于量化无序区域中蛋白质基序保守性的成对k-mer比对

Halpin, Jackson C; Keating, Amy E

Design of Specific Peptide Inhibitors of Toxin-Antitoxin-Mediated Antiphage Defense

针对毒素-抗毒素介导的抗噬菌体防御机制,设计特异性肽抑制剂

Ghose, Dia A; Swanson, Sebastian R; Birnbaum, Foster; Britton, Dustin; Gan, Jessie L; Mahoney, Emily M; Laub, Michael T; Keating, Amy E

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs.

STAT5B 白血病突变改变了 SH2 酪氨酸 665,对免疫基因程序产生了相反的影响

Lee Hye Kyung, Chen Jichun, Philips Rachael L, Lee Sung-Gwon, Feng Xingmin, Wu Zhijie, Liu Chengyu, Schultz Aaron B, Dalzell Molly, Meggendorfer Manja, Haferlach Claudia, Birnbaum Foster, Sexton Joel A, Keating Amy E, O'Shea John J, Young Neal S, Villarino Alejandro V, Furth Priscilla A, Hennighausen Lothar

Elaboration of the Homer1 recognition landscape reveals incomplete divergence of paralogous EVH1 domains

对Homer1识别图谱的详细分析揭示了旁系同源EVH1结构域的不完全分化

Singer, Avinoam; Ramos, Alejandra; Keating, Amy E

Jointly Embedding Protein Structures and Sequences through Residue Level Alignment

通过残基水平比对联合嵌入蛋白质结构和序列

Birnbaum, Foster; Jain, Saachi; Madry, Aleksander; Keating, Amy E