Discovery of BMS-846372, a Potent and Orally Active Human CGRP Receptor Antagonist for the Treatment of Migraine
发现BMS-846372,一种强效且口服有效的CGRP受体拮抗剂,用于治疗偏头痛
期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/ml300021s
Luo, Guanglin; Chen, Ling; Conway, Charles M; Denton, Rex; Keavy, Deborah; Gulianello, Michael; Huang, Yanling; Kostich, Walter; Lentz, Kimberley A; Mercer, Stephen E; Schartman, Richard; Signor, Laura; Browning, Marc; Macor, John E; Dubowchik, Gene M
偏头痛
信号转导
神经科学
多发性硬化症
Human
CGRP