日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Situ Structural Observation of a Substrate- and Peroxide-Bound High-Spin Ferric-Hydroperoxo Intermediate in the P450 Enzyme CYP121

P450酶CYP121中底物和过氧化物结合的高自旋铁氢过氧中间体的原位结构观察

Nguyen, Romie C; Davis, Ian; Dasgupta, Medhanjali; Wang, Yifan; Simon, Philipp S; Butryn, Agata; Makita, Hiroki; Bogacz, Isabel; Dornevil, Kednerlin; Aller, Pierre; Bhowmick, Asmit; Chatterjee, Ruchira; Kim, In-Sik; Zhou, Tiankun; Mendez, Derek; Paley, Daniel W; Fuller, Franklin; Alonso Mori, Roberto; Batyuk, Alexander; Sauter, Nicholas K; Brewster, Aaron S; Orville, Allen M; Yachandra, Vittal K; Yano, Junko; Kern, Jan F; Liu, Aimin

Kinetic and Spectroscopic Characterization of the Catalytic Ternary Complex of Tryptophan 2,3-Dioxygenase

色氨酸2,3-双加氧酶催化三元复合物的动力学和光谱表征

Geng, Jiafeng; Weitz, Andrew C; Dornevil, Kednerlin; Hendrich, Michael P; Liu, Aimin

Biocatalytic Carbon-Hydrogen and Carbon-Fluorine Bond Cleavage through Hydroxylation Promoted by a Histidyl-Ligated Heme Enzyme

通过组氨酸连接血红素酶促进羟基化生物催化碳-氢和碳-氟键断裂

Yifan Wang, Ian Davis, Inchul Shin, Daniel J Wherritt, Wendell P Griffith, Kednerlin Dornevil, Keri L Colabroy, Aimin Liu

Probing Ligand Exchange in the P450 Enzyme CYP121 from Mycobacterium tuberculosis: Dynamic Equilibrium of the Distal Heme Ligand as a Function of pH and Temperature

探测结核分枝杆菌 P450 酶 CYP121 中的配体交换:远端血红素配体随 pH 值和温度变化的动态平衡

Andrew J Fielding, Kednerlin Dornevil, Li Ma, Ian Davis, Aimin Liu

Hypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency

色氨酸2,3-双加氧酶缺乏引起的色氨酸血症

Ferreira, Patrick; Shin, Inchul; Sosova, Iveta; Dornevil, Kednerlin; Jain, Shailly; Dewey, Deborah; Liu, Fange; Liu, Aimin

Tryptophan-mediated charge-resonance stabilization in the bis-Fe(IV) redox state of MauG

色氨酸介导的电荷共振稳定作用使MauG的双Fe(IV)氧化还原态稳定。

Geng, Jiafeng; Dornevil, Kednerlin; Davidson, Victor L; Liu, Aimin

An unexpected copper catalyzed 'reduction' of an arylazide to amine through the formation of a nitrene intermediate

出乎意料的是,铜催化芳基叠氮化物通过形成氮烯中间体而“还原”为胺。

Peng, Hanjing; Dornevil, Kednerlin H; Draganov, Alexander B; Chen, Weixuan; Dai, Chaofeng; Nelson, William H; Liu, Aimin; Wang, Binghe