A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.
一种新型小分子 FL118 以 p53 非依赖的方式选择性抑制 survivin、Mcl-1、XIAP 和 cIAP2,表现出优异的抗肿瘤活性
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0045571
Ling Xiang, Cao Shousong, Cheng Qiuying, Keefe James T, Rustum Youcef M, Li Fengzhi