日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma.

肼屈嗪通过抑制半胱胺双加氧酶来治疗先兆子痫和衰老性胶质母细胞瘤。

Shishikura Kyosuke, Li Jiasong, Chen Yiming, McKnight Nate R, Keeley Thomas P, Bustin Katelyn A, Barr Eric W, Chilkamari Snehil R, Ayub Mahaa, Kim Sun Woo, Lin Zongtao, Hu Ren-Ming, Hicks Kelly, Wang Xie, O'Rourke Donald M, Martin Bollinger J Jr, Binder Zev A, Parsons William H, Martemyanov Kirill A, Liu Aimin, Matthews Megan L

Nitric oxide promotes cysteine N-degron proteolysis through control of oxygen availability.

一氧化氮通过控制氧气供应来促进半胱氨酸 N-降解子的蛋白水解

Kim Haeun, Tian Ya-Min, Ratcliffe Peter J, Keeley Thomas P

Making sense of oxygen sensing

理解氧气传感

Ratcliffe, Peter J; Keeley, Thomas P

Corrigendum to "Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels" [Redox Biol. 53 (2022) 102319]

对“一氧化氮生物传感器揭示了适应生理氧水平的培养细胞对亚铁依赖性的降低”的更正[Redox Biol. 53 (2022) 102319]

Sevimli, Gulsah; Smith, Matthew J; Caglar, Tuba Akgul; Bilir, Şükriye; Secilmis, Melike; Altun, Hamza Y; Yigit, Esra N; Yang, Fan; Keeley, Thomas P; Malli, Roland; Öztürk, Gürkan; Mann, Giovanni E; Eroglu, Emrah

Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation

脑内皮细胞在适应生理氧水平后,Nrf2 调控的氧化还原信号传导:对萝卜硫素介导的抗缺氧-复氧保护作用的影响

Warpsinski, Gabriela; Smith, Matthew J; Srivastava, Salil; Keeley, Thomas P; Siow, Richard C M; Fraser, Paul A; Mann, Giovanni E

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

保守的N端半胱氨酸双加氧酶在动植物中传递对缺氧的反应。

Masson, Norma; Keeley, Thomas P; Giuntoli, Beatrice; White, Mark D; Puerta, Mikel Lavilla; Perata, Pierdomenico; Hopkinson, Richard J; Flashman, Emily; Licausi, Francesco; Ratcliffe, Peter J

Reduced SERCA activity underlies dysregulation of Ca(2+) homeostasis under atmospheric O(2) levels

大气中氧气浓度升高会导致SERCA活性降低,进而引发Ca(2+)稳态失调。

Keeley, Thomas P; Siow, Richard C M; Jacob, Ron; Mann, Giovanni E