日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-Cell Morphomechanics of Prostate Cancer-Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

前列腺癌相关成纤维细胞的单细胞形态力学研究揭示了与患者预后相关的独特特征

Garside, Antje; Jacobi, Angela; Keerthikumar, Shivakumar; Mahajan, Vaibhav; Richards, Michelle; Niranjan, Birunthi; Teng, Linda; Choo, Nicholas; Wei, Johannes Low Jun; Risbridger, Gail P; Lawrence, Mitchell G; Taubenberger, Anna V

Variable cellular and radiobiological effects of [(177)Lu]Lu-PSMA-I&T in patient-derived models of prostate cancer

[(177)Lu]Lu-PSMA-I&T 在前列腺癌患者模型中表现出不同的细胞和放射生物学效应

Everard, Isabel M; de Veer, Michael J; Kwan, Edmond M; Lister, Natalie L; Keerthikumar, Shivakumar; Ryan, Andrew; Sivaratnam, Dinesh; Haskali, Mohammad B; Risbridger, Gail P; Porter, Laura H; Taylor, Renea A

Single-cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

单细胞转录组学将局灶性神经内分泌分化重新定义为一种独特的前列腺癌病理。

Quezada Urban, Rosalia; Keerthikumar, Shivakumar; Clark, Ashlee; Wang, Hong; Phipson, Belinda; Bakshi, Andrew; Ryan, Andrew; Thorne, Heather; Taylor, Renea A; Lawrence, Mitchell G; Risbridger, Gail P; Toivanen, Roxanne; Goode, David L

Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models

低剂量卡铂可改变肿瘤微环境,从而增强CAR-T细胞在人类前列腺癌模型中的疗效

L H Porter # ,J J Zhu # ,N L Lister ,S G Harrison ,S Keerthikumar ,D L Goode ,R Quezada Urban ,D J Byrne ,A Azad ,I Vela ,M S Hofman ,P J Neeson ,P K Darcy ,J A Trapani ,R A Taylor ,G P Risbridger

The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

MURAL 收集前列腺癌患者来源的异种移植模型,可通过泌尿肿瘤学的临床前模型进行发现

Gail P Risbridger #, Ashlee K Clark #, Laura H Porter #, Roxanne Toivanen, Andrew Bakshi, Natalie L Lister, David Pook, Carmel J Pezaro, Shahneen Sandhu, Shivakumar Keerthikumar, Rosalia Quezada Urban, Melissa Papargiris, Jenna Kraska, Heather B Madsen, Hong Wang, Michelle G Richards, Birunthi Niran

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

口服牛奶来源的细胞外囊泡会诱导原发性肿瘤衰老,但会加速癌症转移

Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Shivakumar Keerthikumar, Alex Spurling, Sai V Chitti, Damien Zanker, Ching-Seng Ang, Ishara Atukorala, Taeyoung Kang, Sanjay Shahi, Akbar L Marzan, Christina Nedeva, Claire Vennin, Morghan C Lucas, Lesley Cheng, David Herr

Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment

肥大细胞衍生的 SAMD14 是人类前列腺肿瘤微环境的新型调节剂

Linda K H Teng, Brooke A Pereira, Shivakumar Keerthikumar, Cheng Huang, Birunthi Niranjan, Sophie N Lee, Michelle Richards, Ralf B Schittenhelm, Luc Furic, David L Goode, Mitchell G Lawrence, Renea A Taylor, Stuart J Ellem, Gail P Risbridger, Natalie L Lister

Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity

肠道 Hdac3 的缺失重塑了肠细胞的脂质组并保护小鼠免于饮食引起的肥胖

Mercedes Dávalos-Salas, Magdalene K Montgomery, Camilla M Reehorst, Rebecca Nightingale, Irvin Ng, Holly Anderton, Sheren Al-Obaidi, Analia Lesmana, Cameron M Scott, Paul Ioannidis, Hina Kalra, Shivakumar Keerthikumar, Lars Tögel, Angela Rigopoulos, Sylvia J Gong, David S Williams, Prusoth Yogananth

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

源自患者的阿比特龙和恩扎卢胺耐药性前列腺癌模型揭示了对核糖体靶向治疗的敏感性

Lawrence, Mitchell G; Obinata, Daisuke; Sandhu, Shahneen; Selth, Luke A; Wong, Stephen Q; Porter, Laura H; Lister, Natalie; Pook, David; Pezaro, Carmel J; Goode, David L; Rebello, Richard J; Clark, Ashlee K; Papargiris, Melissa; Van Gramberg, Jenna; Hanson, Adrienne R; Banks, Patricia; Wang, Hong; Niranjan, Birunthi; Keerthikumar, Shivakumar; Hedwards, Shelley; Huglo, Alisee; Yang, Rendong; Henzler, Christine; Li, Yingming; Lopez-Campos, Fernando; Castro, Elena; Toivanen, Roxanne; Azad, Arun; Bolton, Damien; Goad, Jeremy; Grummet, Jeremy; Harewood, Laurence; Kourambas, John; Lawrentschuk, Nathan; Moon, Daniel; Murphy, Declan G; Sengupta, Shomik; Snow, Ross; Thorne, Heather; Mitchell, Catherine; Pedersen, John; Clouston, David; Norden, Sam; Ryan, Andrew; Dehm, Scott M; Tilley, Wayne D; Pearson, Richard B; Hannan, Ross D; Frydenberg, Mark; Furic, Luc; Taylor, Renea A; Risbridger, Gail P

A novel community driven software for functional enrichment analysis of extracellular vesicles data

一种新型的社区驱动型软件,用于对细胞外囊泡数据进行功能富集分析

Pathan, Mohashin; Keerthikumar, Shivakumar; Chisanga, David; Alessandro, Riccardo; Ang, Ching-Seng; Askenase, Philip; Batagov, Arsen O; Benito-Martin, Alberto; Camussi, Giovanni; Clayton, Aled; Collino, Federica; Di Vizio, Dolores; Falcon-Perez, Juan Manuel; Fonseca, Pedro; Fonseka, Pamali; Fontana, Simona; Gho, Yong Song; Hendrix, An; Hoen, Esther Nolte-'t; Iraci, Nunzio; Kastaniegaard, Kenneth; Kislinger, Thomas; Kowal, Joanna; Kurochkin, Igor V; Leonardi, Tommaso; Liang, Yaxuan; Llorente, Alicia; Lunavat, Taral R; Maji, Sayantan; Monteleone, Francesca; Øverbye, Anders; Panaretakis, Theocharis; Patel, Tushar; Peinado, Héctor; Pluchino, Stefano; Principe, Simona; Ronquist, Goran; Royo, Felix; Sahoo, Susmita; Spinelli, Cristiana; Stensballe, Allan; Théry, Clotilde; van Herwijnen, Martijn J C; Wauben, Marca; Welton, Joanne L; Zhao, Kening; Mathivanan, Suresh