日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CRISPR activation for SCN2A-related neurodevelopmental disorders

CRISPR激活治疗SCN2A相关神经发育障碍

Tamura, Serena; Nelson, Andrew D; Spratt, Perry W E; Hamada, Elizabeth C; Zhou, Xujia; Kyoung, Henry; Li, Zizheng; Arnould, Coline; Barskyi, Vladyslav; Krupkin, Beniamin; Young, Kiana; Zhao, Jingjing; Holden, Stephanie S; Sahagun, Atehsa; Keeshen, Caroline M; Lu, Congyi; Ben-Shalom, Roy; Taloma, Sunrae E; Schamiloglu, Selin; Li, Ying C; Min, Lia; Jenkins, Paul M; Pan, Jen Q; Paz, Jeanne T; Sanders, Stephan J; Matharu, Navneet; Ahituv, Nadav; Bender, Kevin J

Arrestin-3 Agonism at Dopamine D(3) Receptors Defines a Subclass of Second-Generation Antipsychotics That Promotes Drug Tolerance

Arrestin-3 对多巴胺 D(3) 受体的激动作用定义了一类促进药物耐受性的第二代抗精神病药物亚类。

Schamiloglu, Selin; Lewis, Elinor; Keeshen, Caroline M; Hergarden, Anne C; Bender, Kevin J; Whistler, Jennifer L

Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells

新皮质锥体细胞 NaV1.2 钠通道丢失导致反常兴奋性增加

Perry W E Spratt, Ryan P D Alexander, Roy Ben-Shalom, Atehsa Sahagun, Henry Kyoung, Caroline M Keeshen, Stephan J Sanders, Kevin J Bender

The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex

自闭症相关基因 Scn2a 影响前额叶皮质的树突兴奋性和突触功能

Perry W E Spratt, Roy Ben-Shalom, Caroline M Keeshen, Kenneth J Burke Jr, Rebecca L Clarkson, Stephan J Sanders, Kevin J Bender

Opposing Effects on Na(V)1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures

对Na(V)1.2功能产生相反影响是自闭症谱系障碍患者或婴儿癫痫患者中观察到的SCN2A变异体之间差异的根本原因。

Ben-Shalom, Roy; Keeshen, Caroline M; Berrios, Kiara N; An, Joon Y; Sanders, Stephan J; Bender, Kevin J

Perspectives of Low Socioeconomic Status Mothers of Premature Infants

低社会经济地位早产儿母亲的视角

Enlow, Elizabeth; Faherty, Laura J; Wallace-Keeshen, Sara; Martin, Ashley E; Shea, Judy A; Lorch, Scott A

Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons

血清素增强小鼠前额叶快速放电中间神经元的兴奋性和伽马频率时间整合

Jegath C Athilingam, Roy Ben-Shalom, Caroline M Keeshen, Vikaas S Sohal, Kevin J Bender