HuM195 and its single-chain variable fragment increase Aβ phagocytosis in microglia via elimination of CD33 inhibitory signaling.
HuM195 及其单链可变片段通过消除 CD33 抑制信号来增加小胶质细胞中的 Aβ 吞噬作用
期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-024-02474-z
Wong Eitan, Malviya Manish, Jain Tanya, Liao George P, Kehs Zoe, Chang Jerry C, Studer Lorenz, Scheinberg David A, Li Yue-Ming
