日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Smooth muscle-derived adventitial progenitor cells direct atherosclerotic plaque composition complexity in a Klf4-dependent manner

平滑肌衍生的外膜祖细胞以 Klf4 依赖的方式指导动脉粥样硬化斑块成分的复杂性

Allison M Dubner, Sizhao Lu, Austin J Jolly, Keith A Strand, Marie F Mutryn, Tyler Hinthorn, Tysen Noble, Raphael A Nemenoff, Karen S Moulton, Mark W Majesky, Mary Cm Weiser-Evans

Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner

平滑肌衍生的外膜祖细胞以 Klf4 依赖的方式促进控制动脉粥样硬化斑块稳定性的关键细胞类型转变

Allison M Dubner, Sizhao Lu, Austin J Jolly, Keith A Strand, Marie F Mutryn, Tyler Hinthorn, Tysen Noble, Raphael A Nemenoff, Karen S Moulton, Mark W Majesky, Mary Cm Weiser-Evans

High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

高通量筛选鉴定出 DNMT1(DNA 甲基转移酶-1)抑制剂 5-氮杂胞苷是 PTEN(磷酸酶和张力蛋白同源物)的强效诱导剂:PTEN 在 5-氮杂胞苷预防病理性血管重塑中发挥着核心作用

Keith A Strand, Sizhao Lu, Marie F Mutryn, Linfeng Li, Qiong Zhou, Blake T Enyart, Austin J Jolly, Allison M Dubner, Karen S Moulton, Raphael A Nemenoff, Keith A Koch, Daniel V LaBarbera, Mary C M Weiser-Evans

PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report

PTEN(磷酸酶和张力蛋白同源物)可抵抗血管紧张素II(Ang II)诱导的病理性血管纤维化和重塑——简报

Sizhao Lu ,Keith A Strand ,Marie F Mutryn ,Rebecca M Tucker ,Austin J Jolly ,Seth B Furgeson ,Karen S Moulton ,Raphael A Nemenoff ,Mary C M Weiser-Evans

Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis

平滑肌来源的祖细胞通过KLF4下调分化为肌成纤维细胞,从而促进动脉重塑和纤维化。

Sizhao Lu ,Austin J Jolly ,Keith A Strand ,Allison M Dubner ,Marie F Mutryn ,Karen S Moulton ,Raphael A Nemenoff ,Mark W Majesky ,Mary Cm Weiser-Evans

Prior voluntary wheel running attenuates neuropathic pain

之前自愿进行跑轮运动可减轻神经性疼痛

Peter M Grace, Timothy J Fabisiak, Suzanne M Green-Fulgham, Nathan D Anderson, Keith A Strand, Andrew J Kwilasz, Erika L Galer, Frederick Rohan Walker, Benjamin N Greenwood, Steven F Maier, Monika Fleshner, Linda R Watkins

Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation

吗啡反而通过增强脊髓 NLRP3 炎症小体的激活延长了大鼠的神经性疼痛

Peter M Grace, Keith A Strand, Erika L Galer, Daniel J Urban, Xiaohui Wang, Michael V Baratta, Timothy J Fabisiak, Nathan D Anderson, Kejun Cheng, Lisa I Greene, Debra Berkelhammer, Yingning Zhang, Amanda L Ellis, Hang Hubert Yin, Serge Campeau, Kenner C Rice, Bryan L Roth, Steven F Maier, Linda R W

Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling

鞘内注射腺苷 2A 受体激动剂可通过蛋白激酶 (PK)A/PKC 信号逆转神经性异常性疼痛

Lisa C Loram, Frederick R Taylor, Keith A Strand, Jacqueline A Harrison, Rachael Rzasalynn, Paige Sholar, Jayson Rieger, Steven F Maier, Linda R Watkins

Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain

利福平通过靶向髓系分化蛋白 2 抑制 Toll 样受体 4 信号传导并减轻神经性疼痛

Xiaohui Wang, Peter M Grace, Michael N Pham, Kui Cheng, Keith A Strand, Christina Smith, Jing Li, Linda R Watkins, Hang Yin

Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy

先前反复使用吗啡会增强由外周炎症和神经病变引起的机械性异常疼痛

Lisa C Loram, Peter M Grace, Keith A Strand, Frederick R Taylor, Amanda Ellis, Debra Berkelhammer, Melissa Bowlin, Bryce Skarda, Steven F Maier, Linda R Watkins