日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease

双特异性TNFα/IL-23中和域抗体作为新型口服治疗炎症性肠病的临床前开发

Kevin J Roberts ,Marion F Cubitt ,Timothy M Carlton ,Lurdes Rodrigues-Duarte ,Luana Maggiore ,Ray Chai ,Simon Clare ,Katherine Harcourt ,Thomas T MacDonald ,Keith P Ray ,Anna Vossenkämper ,Michael R West ,J Scott Crowe

Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients

口服抗肿瘤坏死因子结构域抗体V565可提供高肠道浓度,并降低溃疡性结肠炎患者的炎症标志物。

Suhail Nurbhai ,Kevin J Roberts ,Timothy M Carlton ,Luana Maggiore ,Marion F Cubitt ,Keith P Ray ,Jill Reckless ,Hafeez Mohammed ,Peter Irving ,Thomas T MacDonald ,Anna Vossenkämper ,Michael R West ,Gareth C Parkes ,J Scott Crowe

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

用于治疗炎症性肠病的新型口服抗肿瘤坏死因子结构域抗体的临床前开发

J Scott Crowe, Kevin J Roberts, Timothy M Carlton, Luana Maggiore, Marion F Cubitt, Simon Clare, Katherine Harcourt, Jill Reckless, Thomas T MacDonald, Keith P Ray, Anna Vossenkämper, Michael R West

Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo?

p38 抑制剂抑制类风湿性关节炎滑膜中的细胞因子产生:对白细胞介素 6 产生的不同程度的抑制是否会限制体内有效性?

Theresa H Page, Anthony Brown, Emma M Timms, Brian M J Foxwell, Keith P Ray