文献库，生知库 | 链接生命科学的每一步

Akhir, Fazrena Nadia Md; Noor, Mohd Hezmee Mohd; Leong, Keith Weng Kit; Nabizadeh, Jamileh A; Manthey, Helga D; Sonderegger, Stefan E; Fung, Jenny Nga Ting; McGirr, Crystal E; Shiels, Ian A; Mills, Paul C; Woodruff, Trent M; Rolfe, Barbara E

肿瘤

肿瘤免疫

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The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis

炎症小体适配器 ASC 本质上限制 CD4+ T 细胞增殖以帮助维持肠道稳态

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2019.01566

Hanif Javanmard Khameneh, Keith Weng Kit Leong, Andrea Mencarelli, Maurizio Vacca, Bezaleel Mambwe, Kurt Neo, Alice Tay, Francesca Zolezzi, Bernett Lee, Alessandra Mortellaro

Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes

ASC 的酪氨酸去磷酸化调节 NLRP3 和 AIM2 炎症小体的激活

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2019.01556

Bezaleel Mambwe, Kurt Neo, Hanif Javanmard Khameneh, Keith Weng Kit Leong, Mariasilvia Colantuoni, Maurizio Vacca, Richmond Muimo, Alessandra Mortellaro

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

NLRP10 通过调节树突状细胞来源的 IL-12 释放来增强 CD4+ T 细胞介导的 IFNγ 反应。

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2017.01462

Maurizio Vacca ，Julia Böhme ，Lia Paola Zambetti ，Hanif Javanmard Khameneh ，Bhairav S Paleja ，Federica Laudisi ，Adrian W S Ho ，Kurt Neo ，Keith Weng Kit Leong ，Mardiana Marzuki ，Bernett Lee ，Michael Poidinger ，Laura Santambrogio ，Liana Tsenova ，Francesca Zolezzi ，Gennaro De Libero ，Amit Singhal ，Alessandra Mortellaro

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

鼠伤寒沙门氏菌诱导原代人单核细胞释放IL-1需要NLRP3，且该过程可在无细胞焦亡的情况下发生。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-017-07081-3

Diamond, Catherine E; Leong, Keith Weng Kit; Vacca, Maurizio; Rivers-Auty, Jack; Brough, David; Mortellaro, Alessandra

An Immunoregulatory Role for Complement Receptors in Murine Models of Breast Cancer

补体受体在小鼠乳腺癌模型中的免疫调节作用

The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis

炎症小体适配器 ASC 本质上限制 CD4+ T 细胞增殖以帮助维持肠道稳态

Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes

ASC 的酪氨酸去磷酸化调节 NLRP3 和 AIM2 炎症小体的激活

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

NLRP10 通过调节树突状细胞来源的 IL-12 释放来增强 CD4+ T 细胞介导的 IFNγ 反应。

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

鼠伤寒沙门氏菌诱导原代人单核细胞释放IL-1需要NLRP3，且该过程可在无细胞焦亡的情况下发生。