日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints-A study in asthma

EndoPRS:整合内表型信息以改进临床终点的多基因风险评分——一项哮喘研究

Kharitonova, Elena V; Sun, Quan; Ockerman, Franklin; Chen, Brian; Zhou, Laura Y; Hysong, Micah R; Tuftin, Bjoernar; Cao, Hongyuan; Mathias, Rasika A; Auer, Paul L; Ober, Carole; Raffield, Laura M; Reiner, Alexander P; Cox, Nancy J; Kelada, Samir N P; Tao, Ran; Li, Yun

Culture media influences primary human bronchial epithelial cell morphology, differentiation status, and transcriptional response to ozone exposure

培养基影响原代人支气管上皮细胞的形态、分化状态以及对臭氧暴露的转录反应

Lester, Sarah A; Abdelwahab, Sabri H; Randell, Scott H; Kelada, Samir N P

Evaluating the role of alveolar macrophages in tolerance to ozone

评估肺泡巨噬细胞在臭氧耐受性中的作用

Smith, Gregory J; Nalesnik, Morgan; Immormino, Robert M; Simon, Jeremy M; Harkema, Jack R; Mock, Jason R; Moran, Timothy P; Kelada, Samir N P

Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations

鼻上皮多组学研究揭示了非洲裔人群哮喘风险的三个失调轴

Szczesny, Brooke; Boorgula, Meher Preethi; Chavan, Sameer; Campbell, Monica; Johnson, Randi K; Kammers, Kai; Thompson, Emma E; Cox, Madison S; Shankar, Gautam; Cox, Corey; Morin, Andréanne; Lorizio, Wendy; Daya, Michelle; Kelada, Samir N P; Beaty, Terri H; Doumatey, Ayo P; Cruz, Alvaro A; Watson, Harold; Naureckas, Edward T; Giles, B Louise; Arinola, Ganiyu A; Sogaolu, Olumide; Falade, Adegoke G; Hansel, Nadia N; Yang, Ivana V; Olopade, Christopher O; Rotimi, Charles N; Landis, R Clive; Figueiredo, Camila A; Altman, Matthew C; Kenny, Eimear; Ruczinski, Ingo; Liu, Andrew H; Ober, Carole; Taub, Margaret A; Barnes, Kathleen C; Mathias, Rasika A

Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes

痰液黏蛋白浓度的遗传调控因子及其与慢性阻塞性肺疾病表型的关系

Van Buren, Eric; Radicioni, Giorgia; Lester, Sarah; O'Neal, Wanda K; Dang, Hong; Kasela, Silva; Garudadri, Suresh; Curtis, Jeffrey L; Han, MeiLan K; Krishnan, Jerry A; Wan, Emily S; Silverman, Edwin K; Hastie, Annette; Ortega, Victor E; Lappalainen, Tuuli; Nawijn, Martijn C; Berge, Maarten van den; Christenson, Stephanie A; Li, Yun; Cho, Michael H; Kesimer, Mehmet; Kelada, Samir N P

BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance

BPIFB1 缺失会改变气道黏液的特性并降低黏液纤毛清除功能。

Donoghue, Lauren J; Markovetz, Matthew R; Morrison, Cameron B; Chen, Gang; McFadden, Kathryn M; Sadritabrizi, Taraneh; Gutay, Mark I; Kato, Takafumi; Rogers, Troy D; Snead, Jazmin Y; Livraghi-Butrico, Alessandra; Button, Brian; Ehre, Camille; Grubb, Barbara R; Hill, David B; Kelada, Samir N P

A Locus on Chromosome 15 Contributes to Acute Ozone-induced Lung Injury in Collaborative Cross Mice

15号染色体上的一个基因位点与合作杂交小鼠急性臭氧诱导的肺损伤有关

Tovar, Adelaide; Smith, Gregory J; Nalesnik, Morgan B; Thomas, Joseph M; McFadden, Kathryn M; Harkema, Jack R; Kelada, Samir N P

Integrative analysis reveals mouse strain-dependent responses to acute ozone exposure associated with airway macrophage transcriptional activity

综合分析揭示了小鼠品系对急性臭氧暴露的反应与气道巨噬细胞转录活性相关。

Tovar, Adelaide; Crouse, Wesley L; Smith, Gregory J; Thomas, Joseph M; Keith, Benjamin P; McFadden, Kathryn M; Moran, Timothy P; Furey, Terrence S; Kelada, Samir N P

Regional Differences in Mucociliary Clearance in the Upper and Lower Airways

上下呼吸道黏液纤毛清除的区域差异

Rogers, Troy D; Button, Brian; Kelada, Samir N P; Ostrowski, Lawrence E; Livraghi-Butrico, Alessandra; Gutay, Mark I; Esther, Charles R Jr; Grubb, Barbara R

A Murine Model of Ozone-induced Nonatopic Asthma from the Collaborative Cross

来自合作交叉研究的臭氧诱导非过敏性哮喘小鼠模型

Smith, Gregory J; Tovar, Adelaide; McFadden, Kathryn; Moran, Timothy P; Wagner, James G; Harkema, Jack R; Kelada, Samir N P