日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk

肥胖相关的T细胞功能障碍会损害免疫监视功能并增加患癌风险。

Alexander Piening ,Emily Ebert ,Carter Gottlieb ,Niloufar Khojandi ,Lindsey M Kuehm ,Stella G Hoft ,Kelly D Pyles ,Kyle S McCommis ,Richard J DiPaolo ,Stephen T Ferris ,Elise Alspach ,Ryan M Teague

Loss of mitochondrial pyruvate transport initiates cardiac glycogen accumulation and heart failure

线粒体丙酮酸转运丧失导致心脏糖原积累和心力衰竭

Rachel C Weiss, Kelly D Pyles, Kevin Cho, Michelle Brennan, Jonathan S Fisher, Gary J Patti, Kyle S McCommis

Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes

髓过氧化物酶衍生的次氯酸靶向人类呼吸道上皮血浆蛋白释放蛋白修饰亲电2-氯脂肪醛

Shubha Shakya, Kelly D Pyles, Carolyn J Albert, Rakesh P Patel, Kyle S McCommis, David A Ford

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

通过同源性建模和基于药效团的虚拟筛选鉴定新型线粒体丙酮酸载体抑制剂

Lamees Hegazy, Lauren E Gill, Kelly D Pyles, Christopher Kaiho, Sophia Kchouk, Brian N Finck, Kyle S McCommis, Bahaa Elgendy

Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy

果糖促进黑色素瘤肿瘤的细胞保护和免疫治疗耐药性

Lindsey M Kuehm ,Niloufar Khojandi ,Alexander Piening ,Lauryn E Klevorn ,Simone C Geraud ,Nicole R McLaughlin ,Kristine Griffett ,Thomas P Burris ,Kelly D Pyles ,Afton M Nelson ,Mary L Preuss ,Kevin A Bockerstett ,Maureen J Donlin ,Kyle S McCommis ,Richard J DiPaolo ,Ryan M Teague

Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

新型胰岛素增敏剂 MSDC-0602K 单独使用或与利拉鲁肽联合使用可改善小鼠的胰岛素血症和脂肪肝疾病

Dakota R Kamm, Kelly D Pyles, Martin C Sharpe, Laura N Healy, Jerry R Colca, Kyle S McCommis

Nuclear export factor 3 regulates localization of small nucleolar RNAs

核输出因子3调节小核仁RNA的定位

Melissa W Li, Arthur C Sletten, Jiyeon Lee, Kelly D Pyles, Scot J Matkovich, Daniel S Ory, Jean E Schaffer