日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma

单细胞分析揭示了一种功能异质性的耗竭CD8+ T细胞亚群,该亚群与黑色素瘤对免疫检查点疗法的反应相关。

Kelly M Mahuron # ,Osmaan Shahid # ,Prachi Sao # ,Clinton Wu # ,Alexandra M Haugh ,Laura A Huppert ,Lauren S Levine ,Margaret M Lowe ,Michael Alvarado ,Markee Micu ,Katy K Tsai ,Melissa Chow ,Meromit Singer ,Jason M Schenkel ,Arlene H Sharpe ,Michael D Rosenblum ,Kristen E Pauken ,Adil I Daud

Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

单细胞分析可识别循环抗肿瘤 CD8 T 细胞及其富集标记

Kristen E Pauken #, Osmaan Shahid #, Kaitlyn A Lagattuta #, Kelly M Mahuron #, Jacob M Luber #, Margaret M Lowe, Linglin Huang, Conor Delaney, Jaclyn M Long, Megan E Fung, Kathleen Newcomer, Katy K Tsai, Melissa Chow, Samantha Guinn, Juhi R Kuchroo, Kelly P Burke, Jason M Schenkel, Michael D Rosenbl

Layilin Anchors Regulatory T Cells in Skin

莱伊林锚定皮肤中的调节性T细胞

Pooja Mehta ,Victoire Gouirand ,Devi P Boda ,Jingxian Zhang ,Sofia V Gearty ,Bahar Zirak ,Margaret M Lowe ,Sean Clancy ,Ian Boothby ,Kelly M Mahuron ,Adam Fries ,Matthew F Krummel ,Parminder Mankoo ,Hsin-Wen Chang ,Jared Liu ,Joshua M Moreau ,Tiffany C Scharschmidt ,Adil Daud ,Esther Kim ,Isaac M Neuhaus ,Hobart W Harris ,Wilson Liao ,Michael D Rosenblum

Layilin augments integrin activation to promote antitumor immunity

Layilin 增强整合素活化以促进抗肿瘤免疫

Kelly M Mahuron, Joshua M Moreau #, Jeff E Glasgow, Devi P Boda, Mariela L Pauli, Victoire Gouirand, Luv Panjabi, Robby Grewal, Jacob M Luber, Anubhav N Mathur, Renny M Feldman, Eric Shifrut, Pooja Mehta, Margaret M Lowe, Michael D Alvarado, Alexander Marson, Meromit Singer, Jim Wells, Ray Jupp, Adi

Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues

调节性 T 细胞利用精氨酸酶 2 增强其在组织中的代谢适应性

Margaret M Lowe, Ian Boothby, Sean Clancy, Richard S Ahn, Wilson Liao, David N Nguyen, Kathrin Schumann, Alexander Marson, Kelly M Mahuron, Gillian A Kingsbury, Zheng Liu, Priscila Munoz Sandoval, Robert Sanchez Rodriguez, Mariela L Pauli, Keyon Taravati, Sarah T Arron, Isaac M Neuhaus, Hobart W Har

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells

吲哚-3-甲醇下调端粒酶基因表达需要抑制 hTERT 启动子内的雌激素受体-α 和 Sp1 转录因子相互作用,并介导人类乳腺癌细胞的 G1 细胞周期停滞

Crystal N Marconett, Shyam N Sundar, Min Tseng, Antony S Tin, Kalvin Q Tran, Kelly M Mahuron, Leonard F Bjeldanes, Gary L Firestone