日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The discovery and structural basis of two distinct state-dependent inhibitors of BamA

BamA两种不同的状态依赖性抑制剂的发现及其结构基础

Dawei Sun #,Kelly M Storek #,Dimitry Tegunov #,Ying Yang,Christopher P Arthur,Matthew Johnson,John G Quinn,Weijing Liu,Guanghui Han,Hany S Girgis,Mary Kate Alexander,Austin K Murchison,Stephanie Shriver,Christine Tam,Hiroshi Ijiri,Hiroko Inaba,Tatsuya Sano,Hayato Yanagida,Junichi Nishikawa,Christopher E Heise,Wayne J Fairbrother,Man-Wah Tan,Nicholas Skelton,Wendy Sandoval,Benjamin D Sellers,Claudio Ciferri,Peter A Smith,Patrick C Reid,Christian N Cunningham,Steven T Rutherford,Jian Payandeh

The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding

膜不稳定和蛋白质动力学在 BAM 催化 OMP 折叠中的作用

Paul White #, Samuel F Haysom #, Matthew G Iadanza #, Anna J Higgins, Jonathan M Machin, James M Whitehouse, Jim E Horne, Bob Schiffrin, Charlotte Carpenter-Platt, Antonio N Calabrese, Kelly M Storek, Steven T Rutherford, David J Brockwell, Neil A Ranson, Sheena E Radford

Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies

囊性纤维化痰液中的铜绿假单胞菌聚集体产生胞外多糖,可能会阻碍目前的治疗

Laura K Jennings, Julia E Dreifus, Courtney Reichhardt, Kelly M Storek, Patrick R Secor, Daniel J Wozniak, Katherine B Hisert, Matthew R Parsek

Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate

抗体-抗生素结合物有效杀死铜绿假单胞菌

Kimberly K Kajihara, Homer Pantua, Hilda Hernandez-Barry, Meredith Hazen, Kiran Deshmukh, Nancy Chiang, Rachana Ohri, Erick R Castellanos, Lynn Martin, Marissa L Matsumoto, Jian Payandeh, Kelly M Storek, Kellen Schneider, Peter A Smith, Michael F T Koehler, Siao Ping Tsai, Richard Vandlen, Kelly M L

Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun's Lipoprotein

大肠杆菌脂蛋白二酰甘油转移酶的抑制对布劳恩脂蛋白缺失引起的耐药性不敏感

Jingyu Diao, Rie Komura, Tatsuya Sano, Homer Pantua, Kelly M Storek, Hiroko Inaba, Haruhiko Ogawa, Cameron L Noland, Yutian Peng, Susan L Gloor, Donghong Yan, Jing Kang, Anand Kumar Katakam, Michael Volny, Peter Liu, Nicholas N Nickerson, Wendy Sandoval, Cary D Austin, Jeremy Murray, Steven T Ruther

Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD

大量抗体发现用于探索必需外膜蛋白 LptD 的结构-功能关系

Kelly M Storek, Joyce Chan, Rajesh Vij, Nancy Chiang, Zhonghua Lin, Jack Bevers 3rd, Christopher M Koth, Jean-Michel Vernes, Y Gloria Meng, JianPing Yin, Heidi Wallweber, Olivier Dalmas, Stephanie Shriver, Christine Tam, Kellen Schneider, Dhaya Seshasayee, Gerald Nakamura, Peter A Smith, Jian Payand

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens

LysMD3 是一种 II 型膜蛋白,在体内对多种病原体的反应中不发挥作用

Christine C Yokoyama, Megan T Baldridge, Daisy W Leung, Guoyan Zhao, Chandni Desai, Ta-Chiang Liu, Vladimir E Diaz-Ochoa, Jeremy P Huynh, Jacqueline M Kimmey, Erica L Sennott, Camaron R Hole, Rachel A Idol, Sunmin Park, Kelly M Storek, Caihong Wang, Seungmin Hwang, Ashley Viehmann Milam, Eric Chen, 

A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies

利用大肠杆菌 BamA 的针对性加强和分类免疫策略可识别罕见的生长抑制抗体

Rajesh Vij, Zhonghua Lin, Nancy Chiang, Jean-Michel Vernes, Kelly M Storek, Summer Park, Joyce Chan, Y Gloria Meng, Laetitia Comps-Agrar, Peng Luan, Sophia Lee, Kellen Schneider, Jack Bevers 3rd, Inna Zilberleyb, Christine Tam, Christopher M Koth, Min Xu, Avinash Gill, Marcy R Auerbach, Peter A Smit

Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange

利用两步等位基因交换精确改造铜绿假单胞菌基因组

Laura R Hmelo, Bradley R Borlee, Henrik Almblad, Michelle E Love, Trevor E Randall, Boo Shan Tseng, Chuyang Lin, Yasuhiko Irie, Kelly M Storek, Jaeun Jane Yang, Richard J Siehnel, P Lynne Howell, Pradeep K Singh, Tim Tolker-Nielsen, Matthew R Parsek, Herbert P Schweizer, Joe J Harrison

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix

Pel 是一种阳离子胞外多糖,可交联铜绿假单胞菌生物膜基质中的细胞外 DNA

Laura K Jennings, Kelly M Storek, Hannah E Ledvina, Charlène Coulon, Lindsey S Marmont, Irina Sadovskaya, Patrick R Secor, Boo Shan Tseng, Michele Scian, Alain Filloux, Daniel J Wozniak, P Lynne Howell, Matthew R Parsek