日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A genome-wide CRISPR/Cas9 screen identifies DNA-PK as a sensitiser to 177Lutetium-DOTA-octreotate radionuclide therapy

全基因组 CRISPR/Cas9 筛选确定 DNA-PK 是 177Lutetium-DOTA-octreotate 放射性核素治疗的敏感剂

Kelly Waldeck, Jessica Van Zuylekom, Carleen Cullinane, Twishi Gulati, Kaylene J Simpson, Richard W Tothill, Benjamin Blyth, Rodney J Hicks

Enhancing the anti-tumour activity of 177Lu-DOTA-octreotate radionuclide therapy in somatostatin receptor-2 expressing tumour models by targeting PARP

通过靶向 PARP 增强 177Lu-DOTA-奥曲肽放射性核素治疗在生长抑素受体 2 表达肿瘤模型中的抗肿瘤活性

Carleen Cullinane #, Kelly Waldeck #, Laura Kirby, Buck E Rogers, Peter Eu, Richard W Tothill, Rodney J Hicks

Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model

长期持续暴露于帕比司他可诱导 TH-MYCN 神经母细胞瘤小鼠模型的终末分化和长期存活

Kelly Waldeck, Carleen Cullinane, Kerry Ardley, Jake Shortt, Ben Martin, Richard W Tothill, Jason Li, Ricky W Johnstone, Grant A McArthur, Rodney J Hicks, Paul J Wood

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence

mTORC1 抑制剂依维莫司通过恢复致癌基因诱导的衰老来预防和治疗 Eμ-Myc 淋巴瘤

Meaghan Wall, Gretchen Poortinga, Kym L Stanley, Ralph K Lindemann, Michael Bots, Christopher J Chan, Megan J Bywater, Kathryn M Kinross, Megan V Astle, Kelly Waldeck, Katherine M Hannan, Jake Shortt, Mark J Smyth, Scott W Lowe, Ross D Hannan, Richard B Pearson, Ricky W Johnstone, Grant A McArthur