日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations

小鼠和人类树突状细胞群之间 STING 诱导的激活和细胞死亡不一致

Ee Shan Pang, Ghazal Daraj, Katherine R Balka, Dominic De Nardo, Christophe Macri, Hubertus Hochrein, Kelly-Anne Masterman, Peck S Tan, Angus Shoppee, Zoe Magill, Nazneen Jahan, Mariam Bafit, Yifan Zhan, Benjamin T Kile, Kate E Lawlor, Kristen J Radford, Mark D Wright, Meredith O'Keeffe

Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

人类 CD141+ 树突状细胞 (cDC1) 在晚期黑色素瘤患者中受损,但可以在人源化小鼠模型中作为靶向细胞以增强抗 PD-1

Yoke Seng Lee, Liam J O'Brien, Carina M Walpole, Frances E Pearson, Ingrid M Leal-Rojas, Kelly-Anne Masterman, Victoria Atkinson, Andrew Barbour, Kristen J Radford

Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate naïve and memory NY-ESO-1-specific CD8+ T cells

人类 CLEC9A 抗体将 NY-ESO-1 抗原递送至 CD141+ 树突状细胞,以激活幼稚和记忆性 NY-ESO-1 特异性 CD8+ T 细胞

Kelly-Anne Masterman #, Oscar L Haigh #, Kirsteen M Tullett, Ingrid M Leal-Rojas, Carina Walpole, Frances E Pearson, Jonathon Cebon, Christopher Schmidt, Liam O'Brien, Nikita Rosendahl, Ghazal Daraj, Irina Caminschi, Eric H Gschweng, Roger P Hollis, Donald B Kohn, Mireille H Lahoud, Kristen J Radfor

Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1-specific CD8+ T cells

人源CLEC9A抗体将Wilms肿瘤1(WT1)抗原递送至CD141+树突状细胞,从而激活初始和记忆性WT1特异性CD8+ T细胞。

Frances E Pearson ,Kirsteen M Tullett ,Ingrid M Leal-Rojas ,Oscar L Haigh ,Kelly-Anne Masterman ,Carina Walpole ,John S Bridgeman ,James E McLaren ,Kristin Ladell ,Kelly Miners ,Sian Llewellyn-Lacey ,David A Price ,Antje Tunger ,Marc Schmitz ,John J Miles ,Mireille H Lahoud ,Kristen J Radford