日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma.

抑制 AKT 可增强化疗疗效,并与靶向食管腺癌中的凋亡抑制蛋白产生协同作用

Stevenson Leanne, Cairns Lauren, Li Xiaodun, Jammula Sriganesh, Taylor Harriet, Douglas Rosalie, McCabe Niamh, Gavory Gerald, Jacq Xavier, Fitzgerald Rebecca C, Kennedy Richard D, Harrison Timothy, Turkington Richard C

Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727)

TNT试验(NCT00532727)中,DNA损伤反应和免疫标志物作为转移性三阴性乳腺癌反应预测指标的综合多模态分析

Tovey, Holly; Sipos, Orsolya; Parker, Joel S; Hoadley, Katherine A; Quist, Jelmar; Kernaghan, Sarah; Kilburn, Lucy; Salgado, Roberto; Loi, Sherene; Kennedy, Richard D; Roxanis, Ioannis; Gazinska, Patrycja; Pinder, Sarah E; Bliss, Judith; Perou, Charles M; Haider, Syed; Grigoriadis, Anita; Tutt, Andrew; Cheang, Maggie Chon U

Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer

cGAS-STING介导的免疫反应激活可预测早期乳腺癌新辅助化疗的疗效

Parkes, Eileen E; Savage, Kienan I; Lioe, Tong; Boyd, Clinton; Halliday, Sophia; Walker, Steven M; Lowry, Keith; Knight, Laura; Buckley, Niamh E; Grogan, Andrena; Logan, Gemma E; Clayton, Alison; Hurwitz, Jane; Kirk, Stephen J; Xu, Jiamei; Sidi, Fatima Abdullahi; Humphries, Matthew P; Bingham, Victoria; James, Jaqueline A; James, Colin R; Paul Harkin, D; Kennedy, Richard D; McIntosh, Stuart A

A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours

新型治疗性肽ALM201的首次人体I期剂量递增试验表明,其在未经筛选的卵巢癌和其他晚期实体瘤患者中具有良好的安全性。

El Helali, Aya; Plummer, Ruth; Jayson, Gordon C; Coyle, Vicky M; Drew, Yvette; Mescallado, Nerissa; Harris, Noor; Clamp, Andrew R; McCann, Janine; Swaisland, Helen; Kennedy, Richard D; Cranston, Aaron N; Wilson, Richard H

A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer

一项全面的系统评价和网络荟萃分析:抗血管生成药物在晚期上皮性卵巢癌中的作用

Helali, Aya El; Wong, Charlene H L; Choi, Horace C W; Chan, Wendy W L; Dickson, Naomi; Siu, Steven W K; Chan, Karen K; Ngan, Hextan Y S; Ngan, Roger K C; Kennedy, Richard D

In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer

深入探讨DNA损伤免疫反应作为奥沙利铂治疗结直肠癌的生物标志物的临床和生物学意义

Malla, Sudhir B; Fisher, David J; Domingo, Enric; Blake, Andrew; Hassanieh, Sylvana; Redmond, Keara L; Richman, Susan D; Youdell, Michael; Walker, Steven M; Logan, Gemma E; Chatzipli, Aikaterina; Amirkhah, Raheleh; Humphries, Matthew P; Craig, Stephanie G; McDermott, Ultan; Seymour, Matthew T; Morton, Dion G; Quirke, Philip; West, Nicholas P; Salto-Tellez, Manuel; Kennedy, Richard D; Johnston, Patrick G; Tomlinson, Ian; Koelzer, Viktor H; Campo, Letitia; Kaplan, Richard S; Longley, Daniel B; Lawler, Mark; Maughan, Timothy S; Brown, Louise C; Dunne, Philip D

The clinical and molecular significance associated with STING signaling in breast cancer

STING信号通路在乳腺癌中的临床和分子意义

Parkes, Eileen E; Humphries, Matthew P; Gilmore, Elaine; Sidi, Fatima A; Bingham, Victoria; Phyu, Su M; Craig, Stephanie; Graham, Catherine; Miller, Joseph; Griffin, Daryl; Salto-Tellez, Manuel; Madden, Stephen F; Kennedy, Richard D; Bakhoum, Samuel F; McQuaid, Stephen; Buckley, Niamh E

ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation

ATM激酶抑制剂优先增强PTEN缺陷型前列腺肿瘤细胞对电离辐射的敏感性

Hanna, Conor; Dunne, Victoria L; Walker, Steven M; Butterworth, Karl T; McCabe, Nuala; Waugh, David J J; Kennedy, Richard D; Prise, Kevin M

DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy

乳腺癌DNA修复缺陷:免疫疗法的契机

Gilmore, Elaine; McCabe, Nuala; Kennedy, Richard D; Parkes, Eileen E

The musculoskeletal consequences of latissmus dorsi breast reconstruction in women following mastectomy for breast cancer

乳腺癌根治术后女性背阔肌乳房重建术的肌肉骨骼后果

Blackburn, Nicole E; Mc Veigh, Joseph G; Mc Caughan, Eilis M; Kennedy, Richard D; McIntosh, Stuart A; Wilson, Iseult M