日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic conformational and substrate selectivity profiles emerging in the evolution of enzymes via parallel trajectories

酶通过平行轨迹进化过程中出现的机械构象和底物选择性特征

Christos S Karamitros, Kyle Murray, Yoichi Kumada, Kenneth A Johnson, Sheena D'Arcy, George Georgiou0

Kinetics of elementary steps in loop-mediated isothermal amplification (LAMP) show that strand invasion during initiation is rate-limiting

环介导等温扩增 (LAMP) 中基本步骤的动力学表明,启动过程中的链入侵是限速因素

Tyler L Dangerfield, Inyup Paik, Sanchita Bhadra, Kenneth A Johnson, Andrew D Ellington

Kinetics of DNA strand transfer between polymerase and proofreading exonuclease active sites regulates error correction during high-fidelity replication

聚合酶和校对核酸外切酶活性位点之间的 DNA 链转移动力学调节高保真复制过程中的纠错

Tyler L Dangerfield, Kenneth A Johnson

Substrate specificity and proposed structure of the proofreading complex of T7 DNA polymerase

T7 DNA 聚合酶校对复合物的底物特异性和拟议结构

Tyler L Dangerfield, Serdal Kirmizialtin, Kenneth A Johnson

Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid

使用带有荧光人工氨基酸的 DNA 聚合酶定义错误掺入和错配延伸过程中的构象动力学

Tyler L Dangerfield, Serdal Kirmizialtin, Kenneth A Johnson

Substrate Specificity and Kinetics of RNA Hydrolysis by SARS-CoV-2 NSP10/14 Exonuclease

SARS-CoV-2 NSP10/14 核酸外切酶的 RNA 水解底物特异性和动力学

Tyler L Dangerfield, Kenneth A Johnson

Conformational dynamics during high-fidelity DNA replication and translocation defined using a DNA polymerase with a fluorescent artificial amino acid

使用带有荧光人工氨基酸的 DNA 聚合酶定义高保真 DNA 复制和易位过程中的构象动力学

Tyler L Dangerfield, Kenneth A Johnson

Expression and purification of tag-free SARS-CoV-2 RNA-dependent RNA polymerase in Escherichia coli

大肠杆菌中无标签 SARS-CoV-2 RNA 依赖性 RNA 聚合酶的表达和纯化

Tyler L Dangerfield, Nathan Z Huang, Kenneth A Johnson

Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA

工程化的 CRISPR/Cas9 酶通过减缓 DNA 切割来释放脱靶 DNA,从而提高识别能力

Mu-Sen Liu, Shanzhong Gong, Helen-Hong Yu, Kyungseok Jung, Kenneth A Johnson, David W Taylor

Value-based Healthcare: Health Literacy's Impact on Orthopaedic Care Delivery and Community Viability

以价值为导向的医疗保健:健康素养对骨科医疗服务和社区活力的影响

Furlough, Kenneth A; Johnson, Vietta L; Bozic, Kevin J