日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice

天然免疫球蛋白 M 启动炎症反应,对小鼠肝缺血再灌注损伤和再生都很重要

Keely Marshall, Junfei Jin, Carl Atkinson, Ali Alawieh, Fei Qiao, Biao Lei, Kenneth D Chavin, Songqing He, Stephen Tomlinson

SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes

SphK1 介导高饱和脂肪喂养诱发的 NASH 小鼠模型中的肝脏炎症,并启动肝细胞中的促炎信号传导

Tuoyu Geng, Alton Sutter, Michael D Harland, Brittany A Law, Jessica S Ross, David Lewin, Arun Palanisamy, Sarah B Russo, Kenneth D Chavin, L Ashley Cowart

Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury

在内毒素引起的急性肾损伤中,通过 Toll 样受体 4 依赖的丝裂原活化蛋白激酶激酶/细胞外信号调节激酶信号抑制线粒体的生物合成

Joshua A Smith, L Jay Stallons, Justin B Collier, Kenneth D Chavin, Rick G Schnellmann

Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation

胆红素通过抑制内质网应激和慢性炎症,增加瘦素受体缺陷和饮食诱导的肥胖小鼠的胰岛素敏感性

Huansheng Dong, Hu Huang, Xinxu Yun, Do-sung Kim, Yinan Yue, Hongju Wu, Alton Sutter, Kenneth D Chavin, Leo E Otterbein, David B Adams, Young-Bum Kim, Hongjun Wang

An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: a dose escalation study

健康志愿者体内游离水飞蓟素黄酮木脂素的药代动力学和抗氧化活性评估:剂量递增研究

Hao-Jie Zhu, Bryan J Brinda, Kenneth D Chavin, Hilary J Bernstein, Kennerly S Patrick, John S Markowitz

Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers

诱导型一氧化氮合酶在脂肪肝移植后线粒体去极化和移植物损伤中的作用

Qinlong Liu, Hasibur Rehman, Yasodha Krishnasamy, Venkat K Ramshesh, Tom P Theruvath, Kenneth D Chavin, Rick G Schnellmann, John J Lemasters, Zhi Zhong

Mitochondrial uncoupling protein-2 deficiency protects steatotic mouse hepatocytes from hypoxia/reoxygenation

线粒体解偶联蛋白 2 缺乏可保护脂肪变性小鼠肝细胞免于缺氧/复氧

Zachary P Evans, Arun P Palanisamy, Alton G Sutter, Justin D Ellett, Venkat K Ramshesh, Hubert Attaway, Michael G Schmidt, Rick G Schnellmann, Kenneth D Chavin

Toll-like receptor 4 knockout mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion

Toll 样受体 4 基因敲除小鼠在完全肝缺血/再灌注后,在没有库普弗细胞的情况下,不会发生内皮过度活化

Justin D Ellett, Carl Atkinson, Zachary P Evans, Zainab Amani, Edward Balish, Michael G Schmidt, Rick G Schnellmann, Kenneth D Chavin

Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10

小鼠库普弗细胞通过 IL-10 保护全肝缺血/再灌注损伤和肠充血

Justin D Ellett, Carl Atkinson, Zachary P Evans, Zainab Amani, Edward Balish, Michael G Schmidt, Nico van Rooijen, Rick G Schnellmann, Kenneth D Chavin

Toll-like receptor 4 is a key mediator of murine steatotic liver warm ischemia/reperfusion injury

Toll 样受体 4 是小鼠脂肪肝热缺血/再灌注损伤的关键介质

Justin D Ellett, Zachary P Evans, Carl Atkinson, Michael G Schmidt, Rick G Schnellmann, Kenneth D Chavin