日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intrinsic link between PGRN and Gba1 D409V mutation dosage in potentiating Gaucher disease

PGRN 和 Gba1 D409V 突变剂量之间的内在联系在增强戈谢病中的作用

Yi Lin ,Xiangli Zhao ,Benjamin Liou ,Venette Fannin ,Wujuan Zhang ,Kenneth D R Setchell ,Xiaohong Wang ,Dao Pan ,Gregory A Grabowski ,Chuan-Ju Liu ,Ying Sun

Perinatal Morphine Exposure Leads to Sex-Dependent Executive Function Deficits and Microglial Changes in Mice

围产期吗啡暴露导致小鼠出现性别依赖性的执行功能缺陷和小胶质细胞变化

Brittany L Smith,Tess A Guzman,Alexander H Brendle,Collin J Laaker,Alexis Ford,Adam R Hiltz,Junfang Zhao,Kenneth D R Setchell,Teresa M Reyes

Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice

奥贝胆酸可改善高脂饮食引起的肥胖小鼠艰难梭菌感染的严重程度

Shinsmon Jose, Anindita Mukherjee, Olivia Horrigan, Kenneth D R Setchell, Wujuan Zhang, Maria E Moreno-Fernandez, Heidi Andersen, Divya Sharma, David B Haslam, Senad Divanovic, Rajat Madan

Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease

底物减少疗法可逆转戈谢病细胞模型中的线粒体、mTOR 和自噬改变

Yanyan Peng, Benjamin Liou, Yi Lin, Venette Fannin, Wujuan Zhang, Ricardo A Feldman, Kenneth D R Setchell, Gregory A Grabowski, Ying Sun

Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease

前颗粒蛋白与己糖胺酶 A 相关,可改善 Tay-Sachs 病中的 GM2 神经节苷脂积累和溶酶体储存

Yuehong Chen, Jinlong Jian, Aubryanna Hettinghouse, Xueheng Zhao, Kenneth D R Setchell, Ying Sun, Chuan-Ju Liu

Hepatic MDR3 expression impacts lipid homeostasis and susceptibility to inflammatory bile duct obstruction in neonates

肝脏 MDR3 表达影响新生儿脂质稳态和对炎症性胆管阻塞的易感性

Alexandra N Carey, Wujuan Zhang, Kenneth D R Setchell, Julia R Simmons, Tiffany Shi, Celine S Lages, Mary Mullen, Kaitlin Carroll, Rebekah Karns, Kazuhiko Bessho, Rachel Sheridan, Xueheng Zhao, Susanne N Weber, Alexander G Miethke

Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease

前颗粒蛋白募集 HSP70 至 β-葡萄糖脑苷脂酶并治疗戈谢病

Jinlong Jian, Qing-Yun Tian, Aubryanna Hettinghouse, Shuai Zhao, Helen Liu, Jianlu Wei, Gabriele Grunig, Wujuan Zhang, Kenneth D R Setchell, Ying Sun, Herman S Overkleeft, Gerald L Chan, Chuan-Ju Liu

CNS, lung, and lymph node involvement in Gaucher disease type 3 after 11 years of therapy: clinical, histopathologic, and biochemical findings

戈谢病 3 型治疗 11 年后中枢神经系统、肺和淋巴结受累:临床、组织病理学和生化发现

Thomas A Burrow #, Ying Sun #, Carlos E Prada, Laurie Bailey, Wujuan Zhang, Amanda Brewer, Steve W Wu, Kenneth D R Setchell, David Witte, Mitchell B Cohen, Gregory A Grabowski

Differential Requirements for L-Citrulline and L-Arginine during Antimycobacterial Macrophage Activity

抗分枝杆菌巨噬细胞活性期间对 L-瓜氨酸和 L-精氨酸的差异需求

Shannon M Rapovy, Junfang Zhao, Rebecca L Bricker, Stephanie M Schmidt, Kenneth D R Setchell, Joseph E Qualls

Neuronopathic Gaucher disease: dysregulated mRNAs and miRNAs in brain pathogenesis and effects of pharmacologic chaperone treatment in a mouse model

神经性戈谢病:小鼠模型中脑发病机制中失调的 mRNA 和 miRNA 以及药物伴侣治疗的影响

Nupur Dasgupta, You-Hai Xu, Ronghua Li, Yanyan Peng, Manoj K Pandey, Stuart L Tinch, Benjamin Liou, Venette Inskeep, Wujuan Zhang, Kenneth D R Setchell, Mehdi Keddache, Gregory A Grabowski, Ying Sun