日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies

CX3CR1缺陷诱导的TIL肿瘤限制作为CAR-T疗法在实体恶性肿瘤治疗中的一种新策略

ThuLe Trinh ,William A Adams ,Alexandra Calescibetta ,Nhan Tu ,Robert Dalton ,Tina So ,Max Wei ,Grace Ward ,Elena Kostenko ,Sean Christiansen ,Ling Cen ,Amy McLemore ,Kayla Reed ,Junmin Whitting ,Danielle Gilvary ,Neale Lopez Blanco ,Carlos Moran Segura ,Jonathan Nguyen ,Wendy Kandell ,Xianghong Chen ,Pingyan Cheng ,Gabriela M Wright ,W Douglas Cress ,Jinghong Liu ,Kenneth L Wright ,Sheng Wei ,Erika A Eksioglu

Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes

氧化的线粒体 DNA 与 TLR9 结合,激活骨髓增生异常综合征中的 NLRP3 炎症小体

Grace A Ward, Robert P Dalton 3rd, Benjamin S Meyer, Amy F McLemore, Amy L Aldrich, Nghi B Lam, Alexis H Onimus, Nicole D Vincelette, Thu Le Trinh, Xianghong Chen, Alexandra R Calescibetta, Sean M Christiansen, Hsin-An Hou, Joseph O Johnson, Kenneth L Wright, Eric Padron, Erika A Eksioglu, Alan F Li

Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma

AMV564(一种新型双价双特异性 CD33/CD3 T 细胞接合剂)在体外对 MDS 和黑色素瘤中的 MDSC 进行免疫耗竭

Pingyan Cheng, Xianghong Chen, Robert Dalton, Alexandra Calescibetta, Tina So, Danielle Gilvary, Grace Ward, Victoria Smith, Sterling Eckard, Judith A Fox, Jeanmarie Guenot, Joseph Markowitz, John L Cleveland, Kenneth L Wright, Alan F List, Sheng Wei, Erika A Eksioglu

Histone deacetylase 8 inhibition suppresses mantle cell lymphoma viability while preserving natural killer cell function

组蛋白去乙酰化酶 8 抑制剂可抑制套细胞淋巴瘤活力,同时保留自然杀伤细胞功能

January M Watters, Gabriela Wright, Matthew A Smith, Bijal Shah, Kenneth L Wright

Constitutively Activated DAP12 Induces Functional Anti-Tumor Activation and Maturation of Human Monocyte-Derived DC

组成性激活的 DAP12 诱导人类单核细胞衍生树突状细胞的功能性抗肿瘤激活和成熟

Robert Dalton, Alexandra Calescibetta, Jun Min Zhou, Michelle Maurin, Grace Ward, Thu Le Trinh, Nhan Tu, Danielle Gilvary, Xianghong Chen, Pingyan Cheng, Elena Kostenko, Sheng Wei, Kenneth L Wright, Erika A Eksioglu

Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival

转录延长因子 ELL3 在 B 细胞中先于 ELL2 选择性表达,促进增殖和存活

Lou-Ella M M Alexander, January Watters, Jessica A Reusch, Michelle Maurin, Brook S Nepon-Sixt, Katerina Vrzalikova, Mark G Alexandrow, Paul G Murray, Kenneth L Wright

Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

支持 11-19 富含赖氨酸的白血病 3 (ELL3) 在 B 细胞淋巴瘤细胞系细胞中发挥功能作用的数据

Lou-Ella M M Alexander, January Watters, Jessica A Reusch, Michelle Maurin, Brook S Nepon-Sixt, Katerina Vrzalikova, Mark G Alexandrow, Paul G Murray, Kenneth L Wright

Cellular differentiation regulator BLIMP1 induces Epstein-Barr virus lytic reactivation in epithelial and B cells by activating transcription from both the R and Z promoters

细胞分化调节剂 BLIMP1 通过激活 R 和 Z 启动子的转录,诱导上皮细胞和 B 细胞中的 Epstein-Barr 病毒裂解再激活

Jessica A Reusch, Dhananjay M Nawandar, Kenneth L Wright, Shannon C Kenney, Janet E Mertz

Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA

肿瘤抑制因子结节性硬化症复合物 1 通过 IRF4 和 CIITA 促进 MHC II 类表达,在树突状细胞活化 CD4 T 细胞中发挥关键作用

Hongjie Pan, Thomas F O'Brien, Gabriela Wright, Jialong Yang, Jinwook Shin, Kenneth L Wright, Xiao-Ping Zhong

Hypomethylation and Over-Expression of the Beta Isoform of BLIMP1 is Induced by Epstein-Barr Virus Infection of B Cells; Potential Implications for the Pathogenesis of EBV-Associated Lymphomas

EB 病毒感染 B 细胞可诱发 BLIMP1 β 异构体的低甲基化和过度表达;这可能与 EBV 相关淋巴瘤的发病机制有关

Katerina Vrzalikova, Sarah Leonard, Yichao Fan, Andrew Bell, Martina Vockerodt, Patrik Flodr, Kenneth L Wright, Martin Rowe, Qian Tao, Paul G Murray