日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipidomics profiles in hepatocytes from nonalcoholic steatohepatitis patients differ markedly from in vitro-induced steatotic hepatocytes

非酒精性脂肪性肝炎患者肝细胞的脂质组学特征与体外诱导的脂肪变性肝细胞有显著不同

Thomas Kralj, Raju Khatri, Kenneth R Brouwer, Kim L R Brouwer, Darren J Creek

Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters

肝细胞胆汁转运蛋白表达改变导致米特拉霉素治疗严重肝毒性

Tristan M Sissung, Phoebe A Huang, Ralph J Hauke, Edel M McCrea, Cody J Peer, Roberto H Barbier, Jonathan D Strope, Ariel M Ley, Mary Zhang, Julie A Hong, David Venzon, Jonathan P Jackson, Kenneth R Brouwer, Patrick Grohar, Jon Glod, Brigitte C Widemann, Theo Heller, David S Schrump, William D Figg

Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms

法尼醇X受体激动剂奥贝胆酸和鹅去氧胆酸增加三明治培养的人肝细胞中胆汁酸外流:功能证据和机制

Guo, Cen; LaCerte, Carl; Edwards, Jeffrey E; Brouwer, Kenneth R; Brouwer, Kim L R

Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?

预测肝脏外排转运体介导的药物相互作用:何时测量抑制剂的细胞内游离分数最为合适?

Guo, Cen; Yang, Kyunghee; Liao, Mingxiang; Xia, Cindy Q; Brouwer, Kenneth R; Brouwer, Kim L R

Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes

夹层培养的人肝细胞中的肝细胞分布和转运蛋白与托伐普坦及其代谢物的相互作用

Yang Lu, Jason R Slizgi, Kenneth R Brouwer, Robert L St Claire, Kimberly M Freeman, Maxwell Pan, William J Brock, Kim L Brouwer

Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

托伐普坦及其代谢物对人类肝脏胆汁酸转运蛋白的抑制:导致药物性肝损伤的因素?

Jason R Slizgi, Yang Lu, Kenneth R Brouwer, Robert L St Claire, Kimberly M Freeman, Maxwell Pan, William J Brock, Kim L R Brouwer

Effect of albumin on the biliary clearance of compounds in sandwich-cultured rat hepatocytes

白蛋白对夹层培养大鼠肝细胞胆汁清除化合物的影响

Kristina K Wolf, Kenneth R Brouwer, Gary M Pollack, Kim L R Brouwer