日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural Mechanism of an Efficacy Photoswitch Targeting the β(2)-adrenergic Receptor

靶向β(2)-肾上腺素能受体的高效光开关的结构机制

Stipp, Robin; Bertrand, Quentin; Trabuco, Matilde; Duran-Corbera, Anna; Ignazzitto, Maria Tindara; Glover, Hannah; Stierli, Fabienne; Catena, Juanlo; Carrillo, Melissa; Hartmann, Sina; Seidel, Hans-Peter; Mulder, Matthias; Mason, Thomas; Kondo, Yasushi; Wranik, Maximillian; Appleby, Martin; Sager, Christoph; Sierra, Raymond; Gate, Gregory; Schleissner, Pamela; Cheng, Xinxin; Weinert, Tobias; Cheng, Robert; Mous, Sandra; Beale, John H; Kepa, Michal; Llebaria, Amadeu; Hennig, Michael; Rovira, Xavier; Standfuss, Joerg

Associations of the HER2DX Genomic Test with Biological and Pathologic Features in HER2-Positive Breast Cancer

HER2DX基因组检测与HER2阳性乳腺癌生物学和病理特征的关联

Sanfeliu, Esther; Martínez-Romero, Anabel; Marín-Aguilera, Mercedes; Cobo, Sandra; González-Farré, Blanca; Hernandez-Illan, Eva; Jares, Pedro; Puig-Butillé, Joan Antón; Muñoz, Montserrat; Gómez-Bravo, Raquel; Tapia, Marta; Tebar, Cristina; Saura, Cristina; Escrivà-de-Romaní, Santiago; Soberino, Jesús; Cortés, Javier; Morales, Serafin; Amillano, Kepa; Paré, Laia; Villagrasa, Patricia; Buckingham, Wesley; Pardo, Francisco; Parker, Joel S; Brasó-Maristany, Fara; Ciruelos, Eva; Sánchez-Bayona, Rodrigo; Martinez-Sáez, Olga; Cejalvo, Juan Miguel; Prat, Aleix

Regulation of Cell Proliferation and Migration by Extracellular Phosphatidic Acid

细胞外磷脂酸对细胞增殖和迁移的调控

Gomez-Larrauri, Ana; Benito-Vicente, Asier; Uribe, Kepa B; Martin, Cesar; Gomez-Muñoz, Antonio

Modelling of radiation damage and beam-induced heating of room-temperature samples at extremely high flux MX beamlines

极高通量MX光束线下室温样品辐射损伤和束流诱导加热的建模

Appleby, Martin V; Kepa, Michal W; Winter, Graeme; McAuley, Katherine E; Beale, John H

Elacestrant in Women with Estrogen Receptor-Positive and HER2-Negative Early Breast Cancer: Results from the Preoperative Window-of-Opportunity ELIPSE Trial

雌激素受体阳性、HER2阴性早期乳腺癌女性患者接受Elacestrant治疗:术前治疗窗口期ELIPSE试验结果

Vidal, Maria; Falato, Claudette; Pascual, Tomás; Sanchez-Bayona, Rodrigo; Muñoz-Mateu, Montserrat; Cebrecos, Isaac; Gonzalez-Farré, Xavier; Cortadellas, Tomás; Margelí Vila, Mireia; Luna, Miguel A; Siso, Christian; Amillano, Kepa; Galván, Patricia; Bergamino, Milana A; Ferrero-Cafiero, Juan M; Salvador, Fernando; Espinosa Guerrero, Alejandra; Pare, Laia; Sanfeliu, Esther; Prat, Aleix; Bellet, Meritxell

mTORC2 inhibition reduces tumor burden via STAT1 activation and enhanced response to anti-PD-L1 therapy

mTORC2抑制通过激活STAT1来降低肿瘤负荷,并增强对PD-L1抑制剂治疗的反应。

Gschwendtner, Anna; Schütz, Birgit; Mirea, Madalina A; Eckel, Oliver; Kepa, Mikolaj Z; Fritsch, Stephanie Deborah; Oberle, Raimund; Weichhart, Thomas; Hengstschläger, Markus; Mikula, Mario

Viscoelastic Properties and Enzymatic Degradation of Crosslinked Hyaluronic Acid for Deep Dermal Filler Use

用于深层真皮填充的交联透明质酸的粘弹性及酶促降解

Melero, Alejandro; Andrade Del Olmo, Jon; Martínez de Cestafe, Nagore; Goenaga Ibeas, Claudia; Ucelay López de Heredia, Miguel; Izaguirre, Jon Kepa; Alonso, José María; Pérez González, Raúl

Data-Driven Generation of Conformational Ensembles and Ternary Complexes for PROTAC and Other Chimera Systems

基于数据驱动的PROTAC及其他嵌合体系统构象集合和三元复合物生成

Montisci, Fabio; Friggeri, Laura; Burusco-Goni, Kepa K; McCabe, Patrick; Popovic, Bojana; Cole, Jason C

Apo-state structure of the metabotropic glutamate receptor 5 transmembrane domain obtained using a photoswitchable ligand.

利用光开关配体获得的代谢型谷氨酸受体5跨膜结构域的无配体状态结构

Kondo Yasushi, Hatton Caitlin, Cheng Robert, Trabuco Matilde, Glover Hannah, Bertrand Quentin, Stierli Fabienne, Seidel Hans-Peter, Mason Thomas, Sarma Sivathmika, Tellkamp Friedjof, Kepa Michal, Dworkowski Florian, Mehrabi Pedram, Hennig Michael, Standfuss Joerg

Modelling the prebiotic origins of regulation and agency in evolving protocell ecologies

模拟演化中的原细胞生态系统中调控和能动性的益生元起源

Shirt-Ediss, Ben; Ferrero-Fernández, Arián; De Martino, Daniele; Bich, Leonardo; Moreno, Alvaro; Ruiz-Mirazo, Kepa