日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Osteoarthritis gene therapy: Expanding the scope of genetic therapies

骨关节炎基因疗法:拓展基因疗法的范围

Evans, Christopher H; Ghivizzani, Steven C; Keravala, Annahita; Chalberg, Thomas W; Robbins, Paul D

Acetylcholine receptor based chemogenetics engineered for neuronal inhibition and seizure control assessed in mice

基于乙酰胆碱受体的化学遗传学设计用于小鼠神经元抑制和癫痫控制

Quynh-Anh Nguyen #, Peter M Klein #, Cheng Xie, Katelyn N Benthall, Jillian Iafrati, Jesslyn Homidan, Jacob T Bendor, Barna Dudok, Jordan S Farrell, Tilo Gschwind, Charlotte L Porter, Annahita Keravala, G Steven Dodson, Ivan Soltesz

Matrix metalloproteinase-3 (MMP-3)-mediated gene therapy for glaucoma

基质金属蛋白酶-3(MMP-3)介导的青光眼基因治疗

Jeffrey O'Callaghan, Conor Delaney, Merissa O'Connor, Joseph van Batenburg-Sherwood, Martin Schicht, Elke Lütjen-Drecoll, Natalie Hudson, Sorcha Ni Dhubhghaill, Peter Humphries, Chris Stanley, Annahita Keravala, Thomas Chalberg, Matthew S Lawrence, Matthew Campbell

Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2

嵌合AAV2.7m8载体与亲本AAV2的结构比较

Antonette Bennett, Annahita Keravala, Victoria Makal, Justin Kurian, Brahim Belbellaa, Rangoli Aeran, Yu-Shan Tseng, Duncan Sousa, John Spear, Mehdi Gasmi, Mavis Agbandje-McKenna

Preclinical Evaluation of ADVM-022, a Novel Gene Therapy Approach to Treating Wet Age-Related Macular Degeneration

治疗湿性年龄相关性黄斑变性的新型基因治疗方法 ADVM-022 的临床前评估

Ruslan Grishanin, Brian Vuillemenot, Pallavi Sharma, Annahita Keravala, Judith Greengard, Claire Gelfman, Mark Blumenkrantz, Matthew Lawrence, Wenzheng Hu, Szilárd Kiss, Mehdi Gasmi

Long-term expression of human coagulation factor VIII in a tolerant mouse model using the φC31 integrase system

利用φC31整合酶系统在耐受小鼠模型中长期表达人凝血因子VIII

Chavez, Christopher L; Keravala, Annahita; Chu, Jacqueline N; Farruggio, Alfonso P; Cuéllar, Vanessa E; Voorberg, Jan; Calos, Michele P

Long-term phenotypic correction in factor IX knockout mice by using ΦC31 integrase-mediated gene therapy

利用ΦC31整合酶介导的基因疗法对IX因子敲除小鼠进行长期表型矫正

Keravala, A; Chavez, C L; Hu, G; Woodard, L E; Monahan, P E; Calos, M P

Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity

核定位和流体动力传递诱导的细胞分裂对 phiC31 整合酶活性的影响

L E Woodard, R T Hillman, A Keravala, S Lee, M P Calos

Kinetics and longevity of ΦC31 integrase in mouse liver and cultured cells.

小鼠肝脏和培养细胞中 ΦC31 整合酶的动力学和寿命

Chavez Christopher L, Keravala Annahita, Woodard Lauren E, Hillman Robert T, Stowe Timothy R, Chu Jacqueline N, Calos Michele P

Mutational derivatives of PhiC31 integrase with increased efficiency and specificity

具有更高效率和特异性的PhiC31整合酶突变衍生物

Keravala, Annahita; Lee, Solomon; Thyagarajan, Bhaskar; Olivares, Eric C; Gabrovsky, Vanessa E; Woodard, Lauren E; Calos, Michele P