日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate change

一项基于 CRISPR 技术的全基因组筛选揭示了翻译起始和泛素化在驱动脂肪细胞命运转变中的新需求。

Turn, Rachel E; Hilgendorf, Keren I; Johnson, Carl T; Han, Kyuho; Aziz-Zanjani, Mohammad Ovais; Swails Bollinger, Samuel; Domizi, Pablo; Cheng, Ran; Rabiee, Atefeh; Zhu, Yingdi; Jiang, Zewen; Asthana, Anushweta; Demeter, Janos; Svensson, Katrin J; Bassik, Michael C; Jackson, Peter K

Hyperlipidemia drives tumor growth in a mouse model of obesity-accelerated breast cancer growth.

在肥胖加速乳腺癌生长的小鼠模型中,高脂血症会促进肿瘤生长

Vieira Renan Fl, Sanchez Sawyer R, Arumugam Menusha, Mower Peyton D, Curtin Meghan C, Jackson Abigail E, Gallop Molly R, Wright Jillian, Bowles Alexis, Ducker Gregory S, Hilgendorf Keren I, Chaix Amandine

Prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2

前列腺素E2通过纤毛依赖性激活ROCK2抑制脂肪生成。

Mark D Lee ,Keren I Hilgendorf

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice.

从瘦鼠和肥胖小鼠中分离和培养原代小鼠脂肪细胞

Curtin Meghan C, Jackson Abigail E, Hilgendorf Keren I

Lean breast adipocytes secrete an oxylipin that suppresses breast cancer via ferroptosis

瘦乳腺脂肪细胞分泌一种氧化脂质,该脂质通过铁死亡抑制乳腺癌。

Curtin, Meghan C; Jackson, Abigail E; Brown, Elisabeth A; Maschek, J Alan; Lum, David; Cox, James E; Welm, Alana L; Hilgendorf, Keren I

Hyperlipidemia drives tumor growth in a mouse model of obesity-accelerated breast cancer growth

高脂血症在肥胖加速乳腺癌小鼠模型中促进肿瘤生长

Vieira, Renan Fl; Sanchez, Sawyer R; Arumugam, Menusha; Mower, Peyton D; Curtin, Meghan C; Gallop, Molly R; Wright, Jillian; Bowles, Alexis; Ducker, Gregory S; Hilgendorf, Keren I; Chaix, Amandine

Emerging mechanistic understanding of cilia function in cellular signalling

对纤毛在细胞信号传导中功能的机制性理解正在逐步加深

Hilgendorf, Keren I; Myers, Benjamin R; Reiter, Jeremy F

Zinc-alpha-2-glycoprotein Secreted by Triple-Negative Breast Cancer Promotes Peritumoral Fibrosis

三阴性乳腺癌分泌的锌α-2-糖蛋白促进肿瘤周围纤维化

Surbhi Verma ,Stephanie D Giagnocavo ,Meghan C Curtin ,Menusha Arumugam ,Sandra M Osburn-Staker ,Guoying Wang ,Aaron Atkinson ,David A Nix ,David H Lum ,James E Cox ,Keren I Hilgendorf

Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis

三阴性乳腺癌分泌的锌α-2-糖蛋白(ZAG/AZGP1)促进肿瘤微环境纤维化

Surbhi Verma, Stephanie Dudics Giagnocavo, Meghan C Curtin, Menusha Arumugam, Sandra M Osburn-Staker, Guoying Wang, Aaron Atkinson, David A Nix, David H Lum, James E Cox, Keren I Hilgendorf

BMPER is a marker of adipose progenitors and adipocytes and a positive modulator of adipogenesis

BMPER 是脂肪祖细胞和脂肪细胞的标志物,也是脂肪生成的正调节剂

Jacob D Garritson, Jiabi Zhang, Alan Achenbach, Maroua Ferhat, Emile Eich, Chris J Stubben, Paige L Martinez, Anna R Ibele, Keren I Hilgendorf, Sihem Boudina