日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Human Dental Pulp Stem Cells Modulate Acute Inflammation Kinetics in the AIRmax Murine Model by Sustained TNF-Alpha Suppression and Transient Homing

人牙髓干细胞通过持续抑制TNF-α和短暂归巢来调节AIRmax小鼠模型中的急性炎症动力学

期刊:Cells
影响因子:5.2
doi:10.3390/cells15020189
Policiquio, Bruna de Oliveira; Fonseca, Vivian Gonzaga; Santos Costa, Geovanna; de Souza, Jean Gabriel; Celia Martinez Ibañez, Olga; Ribeiro, Orlando Garcia; Kerkis, Irina
发育与干细胞
炎症
炎症/感染
Immunology/Inflammation
TNF-α
Human
干细胞
细胞生物学
发表日期：2026
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Phase II trial of intravenous human dental pulp stem cell therapy for Huntington's disease: a randomized, double-blind, placebo-controlled study

亨廷顿病静脉注射人牙髓干细胞疗法的II期临床试验：一项随机、双盲、安慰剂对照研究

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04557-2
Fernandes, Joyce Macedo Sanches; Pagani, Eduardo; Wenceslau, Cristiane Valverde; Ynoue, Leandro Hideki; Ferrara, Luciana; Kerkis, Irina
细胞生物学
发育与干细胞
干细胞
发表日期：2025
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A phase I, open-label study of intravenous human dental pulp stem cells (NestaCell®) at two dose levels in patients with Huntington's disease

一项针对亨廷顿病患者的静脉注射人牙髓干细胞（NestaCell®）的I期开放标签研究，采用两种剂量水平。

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04703-w
Fernandes, Joyce Macedo Sanches; Pagani, Eduardo; Wenceslau, Cristiane Valverde; Ynoue, Leandro Hideki; Ferrara, Luciana; Kerkis, Irina
细胞生物学
发育与干细胞
干细胞
发表日期：2025
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From Brain to Blood: Uncovering Potential Therapeutical Targets and Biomarkers for Huntington's Disease Using an Integrative RNA-Seq Analytical Platform (BDASeq(®))

从脑到血：利用整合RNA测序分析平台（BDASeq®）揭示亨廷顿病的潜在治疗靶点和生物标志物

期刊:Cells
影响因子:5.2
doi:10.3390/cells14130976
Dias Pinto, João Rafael; Faustinoni Neto, Benedito; Munhoz, Luciana; Kerkis, Irina; Araldi, Rodrigo Pinheiro
神经科学
发表日期：2025
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Preclinical In Vitro Evaluation of Extracellular Vesicles from Human Dental Pulp Stem Cells for the Safe and Selective Modulation of Anaplastic Thyroid Carcinoma

人牙髓干细胞来源的细胞外囊泡在体外临床前评估中用于安全、选择性地调节间变性甲状腺癌

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26136443
Alievi, Anderson Lucas; Teixeira, Michelli Ramires; da Costa, Vitor Rodrigues; Kerkis, Irina; Araldi, Rodrigo Pinheiro
肿瘤
肿瘤免疫
细胞生物学
甲状腺癌
Human
干细胞
囊泡
发育与干细胞
免疫/内分泌
发表日期：2025
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Selective Modulation of Osteoclast Function by Bothrops moojeni Venom and Its Fractions: Implications for Therapeutic Targeting in Bone Diseases.

矛头蝮蛇毒液及其组分对破骨细胞功能的选择性调节：对骨病治疗靶向的意义

期刊:Toxins
影响因子:4
doi:10.3390/toxins17030141
D'Amélio Fernanda, Vigerelli Hugo, Batista Isabel de Fátima Correia, Araldi Rodrigo Pinheiro, Prieto-da-Silva Álvaro R B, Pimenta Daniel Carvalho, Kerkis Irina
细胞生物学
发表日期：2025
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AI-Enhanced Transcriptomic Discovery of Druggable Targets and Repurposed Therapies for Huntington's Disease

利用人工智能增强转录组学发现亨廷顿病药物靶点和现有疗法

期刊:Brain Sciences
影响因子:2.8
doi:10.3390/brainsci15080865
Araldi, Rodrigo Pinheiro; Dias Pinto, João Rafael; Kerkis, Irina
发表日期：2025
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Impact of substrate choice on human osteoclast differentiation and secretome: Implications for targeted therapeutic development

底物选择对人类破骨细胞分化和分泌组的影响：对靶向治疗开发的启示

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0333180
D'Amélio, Fernanda; Vigerelli, Hugo; Araldi, Rodrigo Pinheiros; da Costa Neves, Adriana; Prieto-da-Silva, Álvaro Rossan de Brandão; Pimenta, Daniel; Kerkis, Irina
细胞生物学
发表日期：2025
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The impact of interleukin-6 (IL-6) and mesenchymal stem cell-derived IL-6 on neurological conditions

白细胞介素-6 (IL-6) 和间充质干细胞来源的IL-6对神经系统疾病的影响

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2024.1400533
Kerkis, Irina; da Silva, Álvaro Prieto; Araldi, Rodrigo Pinheiro
干细胞
发育与干细胞
细胞生物学
IL-6
发表日期：2024
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How does the age of control individuals hinder the identification of target genes for Huntington's disease?

对照组个体的年龄如何阻碍亨廷顿病靶基因的鉴定？

期刊:Frontiers in Genetics
影响因子:2.8
doi:10.3389/fgene.2024.1377237
Dias Pinto, João Rafael; Faustinoni Neto, Benedito; Sanches Fernandes, Joyce Macedo; Kerkis, Irina; Araldi, Rodrigo Pinheiro
发表日期：2024
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