日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1

人类离子通道 TRPM2 通过 E2F1 和 FOXM1 调节神经母细胞瘤细胞存活

Iwona Hirschler-Laszkiewicz, Fernanda Festa, Suming Huang, George-Lucian Moldovan, Claudia Nicolae, Ashna Dhoonmoon, Lei Bao, Kerry Keefer, Shu-Jen Chen, Hong-Gang Wang, Joseph Y Cheung, Barbara A Miller

The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression

人类离子通道 TRPM2 通过调节整合素表达来调节神经母细胞瘤的迁移和侵袭

Lei Bao, Fernanda Festa, Iwona Hirschler-Laszkiewicz, Kerry Keefer, Hong-Gang Wang, Joseph Y Cheung, Barbara A Miller

Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy

瞬时受体电位离子通道 TRPM2 通过调节线粒体功能、ROS 和自噬促进 AML 增殖和存活

Shu-Jen Chen, Lei Bao, Kerry Keefer, Santhanam Shanmughapriya, Longgui Chen, John Lee, JuFang Wang, Xue-Qian Zhang, Iwona Hirschler-Laszkiewicz, Salim Merali, Carmen Merali, Yuka Imamura, Sinisa Dovat, Muniswamy Madesh, Joseph Y Cheung, Hong-Gang Wang, Barbara A Miller

The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation

人类离子通道 TRPM2 通过 Pyk2、CREB 和 MCU 激活来调节神经母细胞瘤细胞存活和线粒体功能

Iwona Hirschler-Laszkiewicz, Shu-Jen Chen, Lei Bao, JuFang Wang, Xue-Qian Zhang, Santhanam Shanmughapriya, Kerry Keefer, Muniswamy Madesh, Joseph Y Cheung, Barbara A Miller

Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics

神经母细胞瘤中人类离子通道 TRPM2 的耗竭表明其通过调节线粒体活性氧和生物能量学在细胞存活中发挥关键作用

Lei Bao, Shu-Jen Chen, Kathleen Conrad, Kerry Keefer, Thomas Abraham, John P Lee, JuFang Wang, Xue-Qian Zhang, Iwona Hirschler-Laszkiewicz, Hong-Gang Wang, Sinisa Dovat, Brian Gans, Muniswamy Madesh, Joseph Y Cheung, Barbara A Miller

A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α

人类离子通道 TRPM2 的剪接变体通过缺氧诱导因子 (HIF)-1/2α 调节神经母细胞瘤肿瘤生长

Shu-jen Chen, Nicholas E Hoffman, Santhanam Shanmughapriya, Lei Bao, Kerry Keefer, Kathleen Conrad, Salim Merali, Yoshinori Takahashi, Thomas Abraham, Iwona Hirschler-Laszkiewicz, JuFang Wang, Xue-Qian Zhang, Jianliang Song, Carlos Barrero, Yuguang Shi, Yuka Imamura Kawasawa, Michael Bayerl, Tianyu

The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin

瞬时受体电位 (TRP) 通道 TRPC3 TRP 结构域和 AMP 活化蛋白激酶结合位点是促红细胞生成素激活 TRPC3 所必需的

Iwona Hirschler-Laszkiewicz, Qin Tong, Kathleen Waybill, Kathleen Conrad, Kerry Keefer, Wenyi Zhang, Shu-Jen Chen, Joseph Y Cheung, Barbara A Miller