Kert相关文献与解析，生知库 | 链接生命科学的每一步

Comprehensive molecular characterization of craniopharyngiomas using whole transcriptome and spatial transcriptomics approaches.

利用全转录组和空间转录组学方法对颅咽管瘤进行全面的分子表征。

Kert Å pela, MatjaÅ¡iÄ Alenka, PiÅ¾em JoÅ¾e, Mlakar Jernej, BoÅ¡njak Matic, Jerala Miha, Kotnik PrimoÅ¾, Faganel Kotnik Barbara, Kitanovski Lidija, Zupan Andrej

肿瘤

发表日期：2025

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New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial

用于治疗成人慢性恰加斯病（类型不明或伴有轻度心脏进展）的苯硝唑新方案（NuestroBen 研究）：一项 III 期随机、多中心非劣效性临床试验方案

期刊:BMJ Open

影响因子:2.3

doi:10.1136/bmjopen-2024-098079

Marques, Tayná; Forsyth, Colin; Barreira, Fabiana; Lombas, Carola; Blum de Oliveira, Bethania; Laserna, Mónica; Molina, Israel; Bangher, Maria Del Carmen; Javier Fernández, Rosmiro; Lloveras, Susana; Fernández, Marisa Liliana; Scapellato, Pablo; Patterson, Patricia; Garcia, Wilson; Ortiz, Lourdes; Schijman, Alejandro; Moreira, Otacilio C; García, Lineth; Viele, Kert; Longhi, Silvia; Vaillant, Michel; Tipple, Craig; Fraisse, Laurent; Silvestre-Sousa, Andrea; Sosa-Estani, Sergio; Pinazo, María-Jesús

发表日期：2025

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Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH)

设计和方法：一项适应性试验，旨在检验感染和脓毒症住院后降低再入院率方法的比较有效性（ACCOMPLISH）

期刊:Contemporary Clinical Trials Communications

影响因子:1.4

doi:10.1016/j.conctc.2025.101504

Mayes, Kristin; Talisa, Victor B; Malito, Adelina; Mayr, Florian B; Williams, Kelly; Char, Kalpana; Wadas, Richard; Lorenzi, Elizabeth; Viele, Kert; Awdish, Rana; Angus, Derek C; Chang, Chung-Chou Ho; Yende, Sachin

Corrigendum to "Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH)" [Contemp. Clinic. Trials Commun. 46 (2025) 101504]

对“一项适应性试验的设计和方法，以检验感染和脓毒症住院后降低再入院率方法的比较有效性（ACCOMPLISH）”的更正[当代临床试验通讯46（2025）101504]

期刊:Contemporary Clinical Trials Communications

影响因子:1.4

doi:10.1016/j.conctc.2025.101520

Strategies to Promote Resiliency: A Randomized Embedded Multifactorial Adaptative Platform (REMAP) Clinical Trial to Study Interventions to Improve Recovery After Surgery in High-Risk Patients

促进韧性的策略：一项随机嵌入式多因素适应平台（REMAP）临床试验，旨在研究改善高危患者术后康复的干预措施

期刊:Annals of Surgery Open

影响因子:

doi:10.1097/AS9.0000000000000566

Reitz, Katherine M; Nassereldine, Hasan; Kennedy, Jason; Zeh, Ryan; Khandwala, Farah; Seymour, Christopher W; Quintana, Melanie; Viele, Kert; Detry, Michelle; Morris, Alison; Methe, Barbara; Zuckerbraun, Brian; Girard, Timothy D; Marroquin, Oscar C; Esper, Stephen; Holder-Murray, Jennifer; Newman, Anne B; Billiar, Timothy R; Berry, Scott; Angus, Derek C; Neal, Matthew D

发表日期：2025

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Epigenetic mechanisms governing cell type specific somatic expansion and toxicity in Huntington's disease.

亨廷顿病中控制细胞类型特异性体细胞扩增和毒性的表观遗传机制

期刊:

影响因子:

doi:10.1101/2025.05.21.653721

Baffuto Matthew, MÃ¤tlik Kert, Ilyashov Isaac, Siantoputri Maria Esterlita, Chetia Hasnahana, Maeda Yurie, Sipos Erika, Darnell Paul, Kus Laura, Carroll Thomas S, Barrows Douglas, Pressl Christina, Didkovsky Nicholas, Heintz Nathaniel

Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum

人类纹状体和小脑中细胞类型特异性 CAG 重复扩增和突变型亨廷顿蛋白的毒性

期刊:Nature Genetics

影响因子:31.7

doi:10.1038/s41588-024-01653-6

Kert Mätlik, Matthew Baffuto, Laura Kus, Amit Laxmikant Deshmukh, David A Davis, Matthew R Paul, Thomas S Carroll, Marie-Christine Caron, Jean-Yves Masson, Christopher E Pearson, Nathaniel Heintz

Identification and prioritisation of tumour antigen candidates from 79 glioblastoma transcriptomes

从79例胶质母细胞瘤转录组中鉴定和优先排序肿瘤抗原候选物

Ethical clinical trial design and differences in treatment effects

伦理临床试验设计及治疗效果差异

Severe Clinical Phenotype in Alport Syndrome Due to 2 COL4A4 Exon-Skipping Events

Alport综合征的严重临床表型是由2个COL4A4外显子跳跃事件引起的

Comprehensive molecular characterization of craniopharyngiomas using whole transcriptome and spatial transcriptomics approaches.

利用全转录组和空间转录组学方法对颅咽管瘤进行全面的分子表征。

New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial

用于治疗成人慢性恰加斯病（类型不明或伴有轻度心脏进展）的苯硝唑新方案（NuestroBen 研究）：一项 III 期随机、多中心非劣效性临床试验方案

Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH)

设计和方法：一项适应性试验，旨在检验感染和脓毒症住院后降低再入院率方法的比较有效性（ACCOMPLISH）

Corrigendum to "Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH)" [Contemp. Clinic. Trials Commun. 46 (2025) 101504]

对“一项适应性试验的设计和方法，以检验感染和脓毒症住院后降低再入院率方法的比较有效性（ACCOMPLISH）”的更正[当代临床试验通讯46（2025）101504]

Strategies to Promote Resiliency: A Randomized Embedded Multifactorial Adaptative Platform (REMAP) Clinical Trial to Study Interventions to Improve Recovery After Surgery in High-Risk Patients

促进韧性的策略：一项随机嵌入式多因素适应平台（REMAP）临床试验，旨在研究改善高危患者术后康复的干预措施

Epigenetic mechanisms governing cell type specific somatic expansion and toxicity in Huntington's disease.

亨廷顿病中控制细胞类型特异性体细胞扩增和毒性的表观遗传机制

Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum

人类纹状体和小脑中细胞类型特异性 CAG 重复扩增和突变型亨廷顿蛋白的毒性