日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation

醛糖还原酶抑制可减轻糖尿病性心肌病，并与心肌脂肪酸氧化减少有关

期刊:Cardiovascular Diabetology
影响因子:8.5
doi:10.1186/s12933-023-01811-w
Keshav Gopal, Qutuba G Karwi, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Liyan Zhang, Qiuyu Sun, Christina T Saed, Sai Panidarapu, Riccardo Perfetti, Ravichandran Ramasamy, John R Ussher, Gary D Lopaschuk
代谢
心肌病
糖尿病
发表日期：2023
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Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation

丙酮酸代谢控制 CD4+ T 细胞活化过程中染色质重塑

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2023.112583
Enric Mocholi, Laura Russo, Keshav Gopal, Andrew G Ramstead, Sophia M Hochrein, Harmjan R Vos, Geert Geeven, Adeolu O Adegoke, Anna Hoekstra, Robert M van Es, Jose Ramos Pittol, Sebastian Vastert, Jared Rutter, Timothy Radstake, Jorg van Loosdregt, Celia Berkers, Michal Mokry, Colin C Anderson, Ryan
代谢
T细胞
发表日期：2023
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The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase

抗精神病药物多巴胺 2 受体拮抗剂二苯基丁基哌啶通过抑制琥珀酰辅酶 A：3-酮酸辅酶 A 转移酶改善实验性肥胖患者的血糖

期刊:Diabetes
影响因子:6.2
doi:10.2337/db22-0221
Seyed Amirhossein Tabatabaei Dakhili, Amanda A Greenwell, Kunyan Yang, Rabih Abou Farraj, Christina T Saed, Keshav Gopal, Jordan S F Chan, Jadin J Chahade, Farah Eaton, Crystal Lee, Carlos A Velázquez-Martínez, Peter A Crawford, J N Mark Glover, Rami Al Batran, John R Ussher
神经
发表日期：2023
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Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase

肌肉酮体氧化缺陷会通过改变线粒体支链氨基转移酶来破坏 BCAA 分解代谢

期刊:American Journal of Physiology-Endocrinology and Metabolism
影响因子:4.2
doi:10.1152/ajpendo.00206.2022
Hamza Mechchate, Abdualrahman Mohammed Abdualkader, James Bradshaw Bernacchi, Keshav Gopal, S Amirhossein Tabatabaei Dakhili, Kunyan Yang, Amanda A Greenwell, Xingxing Kong, Peter A Crawford, Rami Al Batran
代谢
发表日期：2023
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Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis

肌肉 PDH 损失通过丙酮酸-丙氨酸循环和谷氨酰胺分解引起乳酸性酸中毒和适应性补充补偿

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2023.105375
Keshav Gopal, Abdualrahman Mohammed Abdualkader, Xiaobei Li, Amanda A Greenwell, Qutuba G Karwi, Tariq R Altamimi, Christina Saed, Golam M Uddin, Ahmed M Darwesh, K Lockhart Jamieson, Ryekjang Kim, Farah Eaton, John M Seubert, Gary D Lopaschuk, John R Ussher, Rami Al Batran
信号转导
发表日期：2023
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Stimulating myocardial pyruvate dehydrogenase activity fails to alleviate cardiac abnormalities in a mouse model of human Barth syndrome

刺激心肌丙酮酸脱氢酶活性无法缓解人类 Barth 综合征小鼠模型中的心脏异常

期刊:Frontiers in Cardiovascular Medicine
影响因子:2.8
doi:10.3389/fcvm.2022.997352
Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Keshav Gopal, Christina T Saed, Jordan S F Chan, Nick Kazungu Mugabo, Pavel Zhabyeyev, Farah Eaton, Jennifer Kruger, Gavin Y Oudit, John R Ussher
信号转导
WB
Mouse
发表日期：2022
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The anti-anginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin-induced type 2 diabetes

抗心绞痛雷诺嗪对高脂饮食和链脲佐菌素诱发的 2 型糖尿病雄性小鼠的肝脂肪变性无益

期刊:Canadian Journal of Physiology and Pharmacology
影响因子:1.7
doi:10.1139/cjpp-2021-0559
Christina T Saed, Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Keshav Gopal, Farah Eaton, John R Ussher
代谢
糖尿病
WB
发表日期：2022
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FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity

FoxO1 抑制可通过增加心肌丙酮酸脱氢酶活性来缓解 2 型糖尿病相关的舒张功能障碍

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2021.108935
Keshav Gopal, Rami Al Batran, Tariq R Altamimi, Amanda A Greenwell, Christina T Saed, Seyed Amirhossein Tabatabaei Dakhili, M Toni E Dimaano, Yongneng Zhang, Farah Eaton, Gopinath Sutendra, John R Ussher
代谢
糖尿病
发表日期：2021
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Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation

巴特综合征相关心肌病与心肌葡萄糖氧化减少有关

期刊:American Journal of Physiology-Heart and Circulatory Physiology
影响因子:4.1
doi:10.1152/ajpheart.00873.2020
Amanda A Greenwell, Keshav Gopal, Tariq R Altamimi, Christina T Saed, Faqi Wang, Seyed Amirhossein Tabatabaei Dakhili, Kim L Ho, Liyan Zhang, Farah Eaton, Jennifer Kruger, Rami Al Batran, Gary D Lopaschuk, Gavin Y Oudit, John R Ussher
心血管
心肌病
发表日期：2021
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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

匹莫齐特通过抑制骨骼肌酮氧化缓解饮食引起的肥胖症中的高血糖

期刊:Cell Metabolism
影响因子:27.7
doi:10.1016/j.cmet.2020.03.017
Rami Al Batran, Keshav Gopal, Megan E Capozzi, Jadin J Chahade, Bruno Saleme, S Amirhossein Tabatabaei-Dakhili, Amanda A Greenwell, Jingjing Niu, Malak Almutairi, Nikole J Byrne, Grant Masson, Ryekjang Kim, Farah Eaton, Erin E Mulvihill, Léa Garneau, Andrea R Masters, Zeruesenay Desta, Carlos A Velá
代谢
发表日期：2020
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