日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of small molecules that enhance aminoglycoside-mediated suppression of CFTR and NF1 nonsense mutations.

鉴定能增强氨基糖苷类药物对 CFTR 和 NF1 无义突变抑制作用的小分子。

Sammons Joshua, Chen Jianguo, Thrasher Kari, Fu Lianwu, Du Ming, Wen Hui, Bostwick J Robert, Vinson Paige, Moukha-Chafiq Omar, Augelli-Szafran Corinne, Keeling Kim M, Wallis Deeann, Kesterson Robert A, Rowe Steven M, Bedwell David M

Repair of Mutated NF1 mRNA with Trans-Splicing Group I Intron Ribozymes

利用反式剪接组 I 内含子核酶修复突变的 NF1 mRNA

Leier, André; Han, Xu; Aghzadi, Jehanne; Westin, Erik; Liu, Jian; Marquez Lago, Tatiana T; Kesterson, Robert A; Korf, Bruce R; Wallis, Deeann; Müller, Ulrich F

RANK IVVY motif plays crucial roles in osteoclastogenesis.

RANK IVVY 基序在破骨细胞生成中起着至关重要的作用

Chen Shenyuan, Shi Zhenqi, Jules Joel, Li Yuyu, Kesterson Robert A, Elbahoty Mohamed Halaby, Zhang Ping, Feng Xu

NF1 mutation-driven neuronal hyperexcitability sets a threshold for tumorigenesis and therapeutic targeting of murine optic glioma

NF1突变驱动的神经元过度兴奋为小鼠视神经胶质瘤的发生和治疗靶点设定了阈值

Anastasaki, Corina; Chatterjee, Jit; Koleske, Joshua P; Gao, Yunqing; Bozeman, Stephanie L; Kernan, Chloe M; Marco Y Marquez, Lara I; Chen, Ji-Kang; Kelly, Caitlin E; Blair, Connor J; Dietzen, Dennis J; Kesterson, Robert A; Gutmann, David H

Mutation-Directed Therapeutics for Neurofibromatosis Type I

针对I型神经纤维瘤病的突变导向疗法

Leier, Andre; Bedwell, David M; Chen, Ann T; Dickson, George; Keeling, Kim M; Kesterson, Robert A; Korf, Bruce R; Marquez Lago, Tatiana T; Müller, Ulrich F; Popplewell, Linda; Zhou, Jiangbing; Wallis, Deeann

Truncating PKHD1 and PKD2 mutations alter energy metabolism

PKHD1 和 PKD2 截断突变会改变能量代谢

Chumley, Phillip; Zhou, Juling; Mrug, Sylvie; Chacko, Balu; Parant, John M; Challa, Anil K; Wilson, Landon S; Berryhill, Taylor F; Barnes, Stephen; Kesterson, Robert A; Bell, P Darwin; Darley-Usmar, Victor M; Yoder, Bradley K; Mrug, Michal

Updated nomenclature for human and mouse neurofibromatosis type 1 genes

人类和小鼠1型神经纤维瘤病基因的命名法更新

Anastasaki, Corina; Le, Lu Q; Kesterson, Robert A; Gutmann, David H

NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1

NF1种系突变对神经纤维瘤病-1型患者的视神经胶质瘤形成和生长具有不同的决定性作用。

Toonen, Joseph A; Anastasaki, Corina; Smithson, Laura J; Gianino, Scott M; Li, Kairong; Kesterson, Robert A; Gutmann, David H

CRYβA3/A1-Crystallin Knockout Develops Nuclear Cataract and Causes Impaired Lysosomal Cargo Clearance and Calpain Activation.

CRYβA3/A1-晶状体蛋白敲除导致核性白内障,并引起溶酶体货物清除受损和钙蛋白酶激活

Hegde Shylaja, Kesterson Robert A, Srivastava Om P

Coiled-coil domain containing 42 (Ccdc42) is necessary for proper sperm development and male fertility in the mouse

卷曲螺旋结构域蛋白42 (Ccdc42) 对小鼠精子正常发育和雄性生育能力是必需的。

Pasek, Raymond C; Malarkey, Erik; Berbari, Nicolas F; Sharma, Neeraj; Kesterson, Robert A; Tres, Laura L; Kierszenbaum, Abraham L; Yoder, Bradley K