日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Regulation of the endosomal SNX27-retromer by OTULIN

OTULIN 对内体 SNX27-逆转录酶的调控

Aurelia Stangl, Paul R Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T Pfluger, Farid El Oualid, Benedikt M Kessler, David Komander, Daniel Krappmann

Molecular basis and regulation of OTULIN-LUBAC interaction

OTULIN-LUBAC相互作用的分子基础及调控

Paul R Elliott, Sofie V Nielsen, Paola Marco-Casanova, Berthe Katrine Fiil, Kirstin Keusekotten, Niels Mailand, Stefan M V Freund, Mads Gyrd-Hansen, David Komander

Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO

RING指蛋白4中SUMO相互作用基序的多价相互作用决定了SUMO链的特异性。

Keusekotten, Kirstin; Bade, Veronika N; Meyer-Teschendorf, Katrin; Sriramachandran, Annie Miriam; Fischer-Schrader, Katrin; Krause, Anke; Horst, Christiane; Schwarz, Günter; Hofmann, Kay; Dohmen, R Jürgen; Praefcke, Gerrit J K

OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

OTULIN 通过特异性水解 Met1 连接的多泛素来拮抗 LUBAC 信号传导

Kirstin Keusekotten, Paul Ronald Elliott, Laura Glockner, Berthe Katrine Fiil, Rune Busk Damgaard, Yogesh Kulathu, Tobias Wauer, Manuela Kathrin Hospenthal, Mads Gyrd-Hansen, Daniel Krappmann, Kay Hofmann, David Komander

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

OTULIN 限制 Met1 连接的泛素化来控制先天免疫信号

Berthe Katrine Fiil #, Rune Busk Damgaard #, Sebastian Alexander Wagner, Kirstin Keusekotten, Melanie Fritsch, Simon Bekker-Jensen, Niels Mailand, Chunaram Choudhary, David Komander, Mads Gyrd-Hansen

Reconstitution of SUMO-dependent ubiquitylation in vitro

体外重建SUMO依赖性泛素化

Kirstin Keusekotten, Gerrit J K Praefcke

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

三氧化二砷刺激 SUMO-2/3 修饰,导致 RNF4 依赖的 PML 蛋白水解靶向

Stefan R Weisshaar, Kirstin Keusekotten, Anke Krause, Christiane Horst, Helen M Springer, Kerstin Göttsche, R Jürgen Dohmen, Gerrit J K Praefcke