VE-1902-A direct thrombin inhibitor with reversible covalent mechanism of action shows efficacy with reduced bleeding in rodent models of thrombosis
VE-1902-A 是一种具有可逆共价作用机制的直接凝血酶抑制剂,在啮齿动物血栓模型中显示出疗效并能减少出血。
期刊:Thrombosis Research
影响因子:3.4
doi:10.1016/j.thromres.2020.04.020
Sivaraja, Mohanram; Clemens, Daniel M; Sizikov, Sivan; Dash, Subhadra; Xu, Chengpei; Rienzo, Matthew; Yang, Bo; Ryan, Molly; Chattopadhyay, Madhuri; Igoudin, Lev; Chang, Stephanie S; Keutzer, Samuel; Zalicki, Piotr; Estiarte, M Angels; Shiau, Timothy P; Short, Kevin M; Williams, David C; Datta, Anirban; Pozzi, Nicola; Di Cera, Enrico; Gibson, C Michael; Fox, Keith A A; Kita, David B