Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
ONC201治疗H3K27M突变型弥漫性中线胶质瘤的临床疗效是由整合代谢和表观遗传通路紊乱驱动的
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-23-0131
Sriram Venneti # ,Abed Rahman Kawakibi # ,Sunjong Ji # ,Sebastian M Waszak # ,Stefan R Sweha # ,Mateus Mota # ,Matthew Pun # ,Akash Deogharkar ,Chan Chung ,Rohinton S Tarapore ,Samuel Ramage ,Andrew Chi ,Patrick Y Wen ,Isabel Arrillaga-Romany ,Tracy T Batchelor ,Nicholas A Butowski ,Ashley Sumrall ,Nicole Shonka ,Rebecca A Harrison ,John de Groot ,Minesh Mehta ,Matthew D Hall ,Doured Daghistani ,Timothy F Cloughesy ,Benjamin M Ellingson ,Kevin Beccaria ,Pascale Varlet ,Michelle M Kim ,Yoshie Umemura ,Hugh Garton ,Andrea Franson ,Jonathan Schwartz ,Rajan Jain ,Maureen Kachman ,Heidi Baum ,Charles F Burant ,Sophie L Mottl ,Rodrigo T Cartaxo ,Vishal John ,Dana Messinger ,Tingting Qin ,Erik Peterson ,Peter Sajjakulnukit ,Karthik Ravi ,Alyssa Waugh ,Dustin Walling ,Yujie Ding ,Ziyun Xia ,Anna Schwendeman ,Debra Hawes ,Fusheng Yang ,Alexander R Judkins ,Daniel Wahl ,Costas A Lyssiotis ,Daniel de la Nava ,Marta M Alonso ,Augustine Eze ,Jasper Spitzer ,Susanne V Schmidt ,Ryan J Duchatel ,Matthew D Dun ,Jason E Cain ,Li Jiang ,Sylwia A Stopka ,Gerard Baquer ,Michael S Regan ,Mariella G Filbin ,Nathalie Y R Agar ,Lili Zhao ,Chandan Kumar-Sinha ,Rajen Mody ,Arul Chinnaiyan ,Ryo Kurokawa ,Drew Pratt ,Viveka N Yadav ,Jacques Grill ,Cassie Kline ,Sabine Mueller ,Adam Resnick ,Javad Nazarian ,Joshua E Allen ,Yazmin Odia ,Sharon L Gardner ,Carl Koschmann
