日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping

基因组信息场理论 (GIFT) 相对于 GWAS 在基因型-表型映射方面的研究能力

Panagiota Kyratzi, Oswald Matika, Amey H Brassington, Connie E Clare, Juan Xu, David A Barrett, Richard D Emes, Alan L Archibald, Andras Paldi, Kevin D Sinclair, Jonathan Wattis, Cyril Rauch

Developmental exposure to a real-life environmental chemical mixture alters testicular transcription factor expression in neonatal and pre-pubertal rams, with morphological changes persisting into adulthood

发育期暴露于真实环境中的化学混合物会改变新生和青春期前公羊睾丸转录因子的表达,且形态学变化会持续到成年期。

Chris S Elcombe ,Ana Monteiro ,Mohammad Ghasemzadeh-Hasankolaei ,Vasantha Padmanabhan ,Richard Lea ,Kevin D Sinclair ,Neil P Evans ,Michelle Bellingham

Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes

在牛卵母细胞体外成熟过程中去除复杂蛋白质并添加褪黑激素对发育、细胞遗传学和表观遗传学的影响

Desmond A R Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Giuseppe Silvestri, Carla Canedo-Ribeiro, Alan H Handyside, Remi Labrecque, Marc-André Sirard, Richard D Emes, Darren K Griffin, Kevin D Sinclair

Developmental exposure to real-life environmental chemical mixture programs a testicular dysgenesis syndrome-like phenotype in prepubertal lambs

发育期暴露于真实环境中的化学混合物会导致青春期前羔羊出现类似睾丸发育不全综合征的表型

Chris S Elcombe ,Ana Monteiro ,Matthew R Elcombe ,Mohammad Ghasemzadeh-Hasankolaei ,Kevin D Sinclair ,Richard Lea ,Vasantha Padmanabhan ,Neil P Evans ,Michelle Bellingham

Ovine fetal testis stage-specific sensitivity to environmental chemical mixtures

绵羊胎儿睾丸对环境化学混合物的阶段特异性敏感性

Richard G Lea ,Beatrice Mandon-Pépin ,Benoit Loup ,Elodie Poumerol ,Luc Jouneau ,Biola F Egbowon ,Adelle Bowden ,Corinne Cotinot ,Laura Purdie ,Zulin Zhang ,Paul A Fowler ,Kevin D Sinclair

Interspecific Variation in One-Carbon Metabolism within the Ovarian Follicle, Oocyte, and Preimplantation Embryo: Consequences for Epigenetic Programming of DNA Methylation

卵泡、卵母细胞和植入前胚胎内一碳代谢的种间变异:DNA甲基化表观遗传编程的影响

Constance E Clare, Valerie Pestinger, Wing Yee Kwong, Desmond A R Tutt, Juan Xu, Helen M Byrne, David A Barrett, Richard D Emes, Kevin D Sinclair

The fetal ovary exhibits temporal sensitivity to a 'real-life' mixture of environmental chemicals

胎儿卵巢对“真实生活”环境中各种化学物质的混合物表现出时间敏感性。

Richard G Lea ,Maria R Amezaga ,Benoit Loup ,Béatrice Mandon-Pépin ,Agnes Stefansdottir ,Panagiotis Filis ,Carol Kyle ,Zulin Zhang ,Ceri Allen ,Laura Purdie ,Luc Jouneau ,Corinne Cotinot ,Stewart M Rhind ,Kevin D Sinclair ,Paul A Fowler

Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development

绵羊妊娠早期母体蛋白质能量营养不良影响胎儿鸟氨酸循环,从而减少胎儿肾脏微血管发育

Louise J Dunford, Kevin D Sinclair, Wing Y Kwong, Craig Sturrock, Bethan L Clifford, Tom C Giles, David S Gardner

A methyl-deficient diet fed to rats during the pre- and peri-conception periods of development modifies the hepatic proteome in the adult offspring

在发育前和发育围孕期给大鼠喂食缺乏甲基的饮食会改变成年后代的肝脏蛋白质组

Christopher A Maloney, Susan M Hay, Martin D Reid, Gary Duncan, Fergus Nicol, Kevin D Sinclair, William D Rees

B-vitamin and homocysteine status determines ovarian response to gonadotropin treatment in sheep

族维生素和同型半胱氨酸状态决定绵羊卵巢对促性腺激素治疗的反应

Raji Kanakkaparambil, Ravinder Singh, Dongfang Li, Robert Webb, Kevin D Sinclair